Viro: Picornaviridae Flashcards
Pico means?
Very small
Morphology
Small non-enveloped, positive-sense single-stranded
RNA
Replicates in?
Cytoplasm
T/F: Picornaviridae is resistant to inorganic solvents
False: Resistant to many organic solvents
Viral RNA translated into a _____ before
processing
polyprotein
How many genera does Picornaviridae have?
29 genera
Transmitted via?
faecal-oral route ;
may also occur by fomites or by aerosols
Genus largest; contains viruses with the
most relevance to human medicine
Genus Enterovirus
Virion properties of picornaviridae?
Capsid made of 4 structural proteins
Structural protein: Receptor binding, uncoating,
antigenicity
VP1
Structural protein: structural integrity,
immune recognition
VP2 and VP3
Structural protein: RNA encapsidation,
uncoating/pore formation
VP4
What genus is foot and mouth diease
Genus Aphthovirus
Foot-and-Mouth Disease serotypes
7 serotypes: A, O, C, SAT 1, SAT 2, SAT 3, Asia
1
Foot-and-Mouth Disease is endemic in?
Africa, Asia and Middle East
Foot-and-Mouth Disease Infects a wide variety of?
cloven-hoofed
domestic and wild animal species
Foot-and-Mouth Disease does not affect this animal.
Horses are not susceptible
Foot-and-Mouth Disease is most severe in?
Most severe in cattle and swine
T/F: Foot-and-Mouth Disease Virus crosses the placenta
False: Virus does not cross the placenta
