Viral Pathogens Flashcards
1
Q
Hantavirus
A
Surged in years following a drought, heavy rains, lead to an increase in the animal reservoirs. Transmitted through inhalation of virus in rodent excrement
2
Q
Hep A
A
- ssRNA
- Fecal-oral transmission
- Not chronic
- No treatment
- Vaccine available
3
Q
Hep B
A
- dsDNa
- body fluid transmission
- 10% chance of being chronic
- antiviral treatment
- vaccine available
4
Q
Hep C
A
- ssRNA
- blood transfusions transmission
- greater than 50% chance of being viral
- antiviral treatment available
5
Q
HIV
A
- enveloped retrovirus
- positive ssRNA
- virus attaches to CD4 receptor on macrophage
6
Q
AIDS
A
- Destruction of T-h cells (halting antibody production
- spike proteins (gp120) displayed on infected cells bind to CD4 proteins on uninfected cells forming syncytia
7
Q
HAART
A
The use of multiple drugs that act on different viral targets (reverse transcriptase inhibitors and protease inhibitors)
8
Q
High mutation rate of HIV
A
- Reverse transcriptase is error prone
- No proofreading
