Immune System Flashcards

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1
Q

Cytokines

A

Small regulatory proteins that are released by cells and act on other cells to generate and modulate an immune response

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2
Q

Leukocytes

A

White blood cells that arise from bone marrow

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3
Q

Lymphocytes

A

T and B cells

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4
Q

Humoral/Antibody mediated adaptive immunity

A

-antigen presented with MHC II (on immune cells)
-Good against extracellular pathogens
-CD4 mediated
TFH cells activate B cells which differentiate into plasma and memory cells

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5
Q

Cell mediated adaptive immunity

A
  • infected cells present antigens with MHC class I (found on all cells)
  • good against virally infected cells and cancer cells
  • CD8 T cells recognize the antigen
  • kills infected cells using perforins and enzymes
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6
Q

Opsonization

A

Pathogen coated with antibodies to enhance phagocytosis

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7
Q

Purified component vaccines

A
  • capsular polysaccharides
  • conjugate to a protein carrier so an immune response is generated
  • antibodies to polysaccharide mediated opsonization
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8
Q

Attenuated Vaccines

A
  • live but avirulent
  • can be bacterial or viral
  • indices cell mediated immunity
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