Antibiotics Flashcards
1
Q
Bacteriostatic drugs
A
Used to prevent bacterial growth
2
Q
Bactericidal drugs
A
Kill the target microbe
3
Q
An ideal antibiotic
A
- selective toxicity
- no allergic reaction
- few side effects
- soluble in body fluids
- durable/stable in the body
- resistance is difficult to obtain
4
Q
Cell wall synthesis
A
Inhibition of peotidoglycan synthesis (penicillin and vancomycin)
5
Q
Protein synthesis
A
Stops translation of mRNA to protein (streptomycin and erythromycin)
6
Q
Membrane integrity
A
Cell membrane dissolution, cell lysis (Rifampin and ciprofloaxin)
7
Q
Metabolic inhibition
A
Stops key metabolic processes in bacteria (sulfa drugs)
8
Q
Mechanisms of resistance
A
- alteration of drug target
- degradation of antibiotics
- modification of antibiotics
- pump antibiotics out of the cell
