viral infections Flashcards
enteroviruses
resistant to stomach acid and disinfection
fecal-oral spread
leading cause of aseptic meningitis
poliomyelitis
enterovirus
S/S:
mild disease
flaccid paralysis
post-polio syndrome
replicates in motor neurons of anterior horn
live attenuated vaccine can revert
mumps
-ssRNA
syncytia
most common cause of aseptic meningitis/encephalitis in unimmunized
measles
variant causes subacute sclerosing panencephalitis (6yr latency)
vaccine exists
influenza
vaccine exists
herpes (usually HSV2)
reactivation
primary infection
rabies
retrograde movement within neurons
arbovirus
arthopod vector
human is dead-end host
togavirus
arbovirus
enveloped +ssRNA
alphavirus (EEE, WEE, VEE)
togavirus
high fatality rate
uncommon
flavivirus: St louis encephalitis
enveloped +ssRNA
less fatal
West Nile
mild illness
severe infection
bird amplifier
bunyavirus: LaCrosse virus
arbovirus
enveloped -ssRNA
segmented
Midwest, Midatlantic, SE
woody areas
small mammal host
most common cause of arbovirus encephalitis
reovirus: Colorado Tick Fever virus
arbovirus
dsRNA
12 segments
double capsid
western, NW
infect erythroid precursor cells
benign disease
neuronal infection
dermacenter andersoni tick
small rodent host
arenavirus: lymphocytic choriomeningitis virus
arbovirus
-ssRNA
enveloped
helical nucleocapsids
flulike symptoms
meningoencephalitis
immunological tolerance
house mice
