Viral Hemorrhagic Fevers Quickie Flashcards
What causes lassa?
Rodent to human (multi a.m. mate rat
What are the phases of hantavirus?
Febrile, hypotensive, oliguric, diuretic, convalescent
What phase of hantavirus has, bleeding tendency caused by uremia w/ thrombocytopenia? Palatal petechiae?
Oliguric
Very high fever (105.8), HA, retro-orbital pain, N/V, truncal scarlatina rash, myalgia, arthralgias, bleeding nose and gums, and abdominal pain?
Dengue fever
Phases of yellow fever and their characteristics?
Acute: fever, HA/bilious vomiting, conjuntival injection for 3 days
24 hr remission, saddle back
Toxic phase: tons of shit, Brady Cardin, arrhythmia, swelling, petechiae, hematemeiss, epistaxis, jaundice, dark urine, stool changes
Black water vomit?
Yellow fever
What phase of hanta virus has absolute bradycardia?
Febrile phase
What is the treatment for Lassa?
Ribavirin
Ghost like facies late in disease, bleeding fro puncture site, bleeding from GI tract, tachypnea
Ebola
AST levels are much higher than ALT levels
Lassa
Where is dengue?
Tropics
What is the treatment for Crimean Congo?
Ribavirin, supportive care
Where is lassa?
West Africa Nigeria, Sierra Leone, Guinea, and Liberia
Where is Ebola and marburg?
Uganda
Insidious onset 1-3 weeks, fever, joint/lumbar pain, prostration, deafness?
Lassa
Hemorrhagic fever w/ renal failure syndrome?
Hantavirus
Virus replicates in the reticuloendothelial system. Viremia occurs and the immune system is over whelmed leading to jaundice?
Yellow fever
Where is crimea-Congo hemorrhagic fever?
Africa, Asia, Middle East, Eastern Europe
Fever, hemorrhage, renal insufficency in child under 15
Hanta virus
Wha phase of hantavirus has tachcardia signaling impending shock, paralytic ileus, and purposeless mvmts?
Hypotensive
What is the treatment for Hantavirus?
Maintain fluid and electrolyte, ribavirin
What are the two types of mosquitoes that cause yellow fever?
Epidemic/urban (aedes aegypti), sylvatic/jungle (various mosquitoes)
What is the mosquito for dengue fever?
Aedes aegypti (or albopictus), domestic, day biter
Hiccups and tachypnea are noted in these terminally ill patients?
Ebola and marburg
Where is Ebola?
Uganda, and DRC
What causes Crimean Congo?
Ticks, viremic livestock, infected patients body fluids
Flu like symptoms, 3-5 days hemorrhage, MASSIVE ECCHYMOSIS, hepatomegaly, ERYTHEMA (pharynx, face, conjunctiva, neck)
Crimean Congo
Where does hantavirus virus occur?
Far East
Dengue fever MC metabolic change?
Hyponatremia
Severe HA, pharyngitis, arthralgias and myalgia, fever, Asthenia, maculopapular rash, followed by GI symptoms
Ebola
Rash, petechiae/ purpura, conjunctival injection, pharyngeal injection, generalized lymphadenopathy, hepatomegaly?
Dengue fever
Virus usually spread in health care/ lab setting, and human to human in acute stage only?
Ebola and Marburg
What is the treatment for Ebola and marburg?
Isolation, fluids, human convalescent plasma, ZMAPP
When is lassa very bad?
Third trimester
Causes swollen baby syndrome
Lassa
What is the treatment for yellow fever?
Supportive, immunization, isolation of patients, FFP FOR BLEEDING
Fillvirus is what?
Ebola
What is the treatment for dengue?
DF: self limited (acetaminophen)
DHF/ DSS: (admission for IV fluid administration, WHOLE BLOOD TRANSFUSION, drop in HCT of 10%=significant hemorrhage)
Hemorrhagic rash appears over entire body?
Ebola
What is the natural reservoir of Ebola and marburg?
Bats
Fever abates for a day then returns, “saddle back fever”
Dengue
What effects humans and non human primates?
Ebola and Marburg
Petechiae and bleeding at venipuncture?
Dengue fever
Tourniquet test/ what virus?
Dengue/ 20 per sq. Inch
