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Microbiology > Viral Etiology Of Tumors > Flashcards

Viral Etiology Of Tumors Flashcards

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Biology 101 flashcards
1
Q

Mention 7 things that may cause cancer.

A 
Viruses
Environment
Diet
Genetics 
Age
Immune system
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2
Q

How may viruses cause cancer?

A

Some viral genetic information carried in the Nucleic Acids of the virus may enter the chromosome of the infected cell and cause malignancy

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3
Q

The ____ century saw the first descriptions of cancer-causing viruses

A

20th century

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4
Q

________ & ________ are retroviruses in the category that were discovered

A

Avian Sacroma virus/Rous

Avian Leukaemia virus/Ellerman & Bang

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5
Q

Who discovered that retroviruses cause tumors in mice?

A

Ludwig Goss in 1950

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6
Q

_______________ discovered Feline Leukemia virus

A

William Jarrett

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7
Q

Human T lymphotropic virus is associated with ________ cancer

A

Adult T cell leukemia

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8
Q

HTLV is spread transmitted by?

A

Blood Transfer

Breast milk

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9
Q

What is HTLV1 mechanism of action?

A

It drives cell growth through the expression of a particular viral protein “Tax” in latently-infected cells

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10
Q

HTLV is a ________ virus

A

Retrovirus

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11
Q

Epstein-Barr virus is a virus of _______ family.

A

Herpes family

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12
Q

EBV is also known as _____________

A

Human Herpesvirus 4

HHV4

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13
Q

Other viruses that being to the Herpes family include?

A
  1. Herpes Simplex Virus

2. Cytomegalovirus

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14
Q

EBV-linked malignancies include?

A
  1. Burkitt’s lymphoma

2. Nasopharyngeal Carcinoma

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15
Q

A form of skin cancer often associated with AIDS is known as?

A

Kaposi’s sacroma

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16
Q

Mention the common sites Kaposi’s sacroma can be found.

A

Upper body: Head, Neck & Back

Uncommonly: Soft palate, gums

Advanced: Lymph nodes, Lungs, Stomach, Intestines

17
Q

What virus is associated with Cervical Cancer?

A

Human Papillomavirus

18
Q

Hepatitis B is a ________ stranded ______ virus in the ___________ family

A
  1. Double
  2. DNA
  3. Hepadnaviridae
19
Q

Mention the HBV genomes and what they encode

A

Pol-DNA polymerase
Env-Envelope Protein
Pre-core-Pre-core protein
X-May be involved in the activation of host cell genes and development of cancer

20
Q

What cancer could Hepatitis B virus cause?

A

Hepatocellular Carcinoma, which affects patients with chronic hepatitis

21
Q

Mention the risk factors for Heptacellular Carcinoma

A

Hepatitis B & C infection
Alcoholism
Aflatoxins

Microbiology (11 decks)

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