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Microbiology > Enterobacteriaceae > Flashcards

Enterobacteriaceae Flashcards

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Biology 101 flashcards
1
Q

Describe the enterobacteriaceae family

A

Gram negative bacilli

Facultative anaerobes

Ferment glucose with acid production

Reduce nitrates to nitrites

Oxidase -ve

Grow on MacConkey agar

Non-sporing, non-acid fast

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2
Q

Describe the antigenic structure of the enterobacteriaceae family

A

K/Capsular antigens:

Capsular polysaccharide
Heavy in Klebsiella

H/Flagella antigens:

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3
Q

All enterobacteriaceae are motile except❓

A

Shigella

Klebsiella

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4
Q

All enterobacteriaceae are non-capsulated except❓

A

Klebsiella

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5
Q

List some examples of enterobacteriaceae

A

Escherichia

Shigella

Salmonella

Klebsiella

Enterobacter

Citrobacter

Serratia

Proteus

Morganella

Providencia

Erwinia

Yersinia

Edwardsiella

Hafnia

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6
Q

What are examples of enterobacteriaceae that infect the CNS❓

A

E. coli

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7
Q

What are examples of enterobacteriaceae that infect the lower respiratory system❓

A

E. coli

Klebsiella

Enterobacter

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8
Q

What are examples of enterobacteriaceae that infect the blood stream❓

A

E. coli

Klebsiella

Enterobacter

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9
Q

What are examples of enterobacteriaceae that infect the GIT❓

A

Salmonella

Shigella

Yersinia

E. coli

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10
Q

What are examples of enterobacteriaceae that infect the urinary tract❓

A

E. coli

Proteus

Providentia

Klebsiella

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11
Q

What are the site of infections for the enterobacteriaceae family❓

A

CNS

Lower respiratory system

Blood stream

GIT

Urinary tract

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12
Q

E. coli…

  1. Has which three antigens❓
  2. Attach to epithelial surfaces using❓
A

1.
O-liposaccharide
K-capsule
H-flagellum

  1. Pili
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13
Q

What is the clinical significance of E.coli❓

A

UTI (esp in women)

Meningitis in infants (E. coli and grp B. strep)

Diarrhea in infants (EPEC)

Travelers diarrhea (ETEC)

Bloody diarrhea (EHER)

Dysentery-like Syndrome (EIEC)

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14
Q

Diarrhea caused by EPEC is not bloody

True or false

A

True

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15
Q

What does EAEC cause❓

A

Travellers Diarrhea

Persistent diarrhea in young children

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16
Q

What dxs will…

  1. EPEC
  2. ETEC
  3. EHEC
  4. EIEC
  5. EAEC

lead to❓

A

EPEC- Watery diarrhea in infants

ETEC- Watery diarrhea

EHEC- Bloody diarrhea, hemorrhagic colitis and HUS

EIEC- Bloody diarrhea

EAEC- persistent watery diarrhea

17
Q

How does salmonella typhi cause diseases❓

A

By invading macrophages of the intestinal lymphoid tissue (Peyer’s patches)

Spread to reticuloendothelial system and gallbladder

18
Q

“Rose spots” is associated with typhoid fever

True or false

A

True

19
Q

Salmonella thyphi is only transmitted via the oral-fecal route

True or false

A

True

20
Q

How can infections by shigella be transmitted❓

A

Contaminated food and water/contaminated stools

21
Q

What are the two clinically important shigella sps❓

A

Shigella sonnei

Shigella dysenteriae

22
Q

Shigella sonnei typically causes infections where❓

A

Mucosa of the large intestine

Rarely penetrates the deeper intestinal layers

23
Q

Shigella dysenteriae typically causes infections where❓

A

Invades the colonic mucosa

Produces exotoxins (Shiga toxin) w cytotoxic properties

24
Q

Shigellosis is characterised by

A

Diarrhea w blood, mucus and painful abdominal cramping

25
Q

Yersinia pestis…

  1. Is transmitted by❓
  2. Spreads through which system❓
  3. Has an incubation period of❓
  4. Results in❓
A
  1. Fleas/Contaminated animal tissues
  2. Lymph nodes and phagocytes

2-8days

  1. Bubonic/Septicemic plague
26
Q

Enterobacter frequently colonizes hospitalized pts

True or false
What dx can it lead to❓

A

True

Associated w catheters and invasive procedures

May infect burns, wounds, respiratory and urinary tracts

27
Q

What infections are associated with Klebsiella pneumonia and oxytoca ❓

A

Necrotizing lobar pneumonia

UTI

Bacteremia

28
Q

Which species of serratia causes human infections❓

What infections can it cause❓

Which other enterobacteriaceae cause extraintestinal infections❓

A

Serratia marcescens

Extraintestinal infections of lower respiratory and urinary tract

Proteus
Providencia
Morganella

Microbiology (11 decks)

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