Viral Cell Biology

Question 1

Virion

Answer 1

extracellular form protein encapsulated DNA or RNA

Question 2

What do viruses infect?

Answer 2

animals, plants, fungi and bacteria

Question 3

Viruses self assemble

Answer 3

Protein coat (Capsid) contains few proteins that self assemble
Capsid protects the RNA/DNA of virus
Determines the shape of the virus particle

Question 4

Naked virus

Answer 4

Protein coat, nuclei acid and enzymes i.e. adenovirus

Question 5

Enveloped virus

Answer 5

Protein coat, nuclei acid, enzymes, biomembrane and enveloped proteins
HIV

Question 6

Complex virus

Answer 6

Protein coat, nuclei acid, enzymes, tail

T4 Phage

Question 7

How can viruses enter the host cell?

Answer 7

Endocytosis (Trojan horse) (, membrane fusion and injection (inject genetic info)

Question 8

t4 bacteriophage

Answer 8

25 structural proteins and double stranded DNA

injection apparatus is contractile

Question 9

Life cycle of a bacteriophage

Answer 9

Virus attaches to surface receptors, tail contracts, lytic enzymes break cell wall and core needle pinches cell, content of the head is released into the cell
Metabolism is disrupted and the genomic DNA degraded
viral DNA is transcribed into mRNA
viral DNA is replicated
mRNA is translated
Virus self assembles

Question 10

Life cycle of an enveloped virus

Answer 10

Binding, endocytosis, transport uses dynein to get info to nucleus

Question 11

Which give the longest transport?

Answer 11

microtubules

Question 12

What do antibodies do?

Answer 12

Bind to target protein i.e. dynein sub protein so dynein cannot operate and inactivate this by injecting antiobdies

Question 13

What does viral replication require?

Answer 13

microtubules and F-actin