Mid-term test Flashcards

1
Q

What is Antony Van Leeuwenhoek famous for?

A

Microbes using a simple microscope

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2
Q

S-Phase of a cell is when

A

DNA is replicated

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3
Q

What do Bacteria, Archaea, fungi, plant, protists and animal cells have in common?

A

A plasma membrane

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4
Q

According to the “RNA world hypothesis” the protocell had which features?

A

It was surrounded by a lipid bilayer

IT contained ribozymes and RNA

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5
Q

What is a cellular compartment?

A

An organelle that performs a specific cellular function which is surrounded by a membrane and secreted into the extracellular space

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6
Q

What isn’t found in prokaryotes?

A

Golgi apparatus

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7
Q

What is FRAP?

A

Visualises cellular dynamics

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8
Q

what does the plasma membrane contain?

A

Phospholipids, integral protein, glycoproteins and steroids

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9
Q

A pump in the plasma membrane has what properties?

A

It uses ATP to transport ions against their conc gradient and it transports ions

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10
Q

Which structures confer resistance against shear forces and thereby strengthen epithelial tissues?

A

Desmosomes, Hemidesmosomes and tight junctions

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11
Q

Which compounds are part of an intracellular signalling pathway?

A

Intracellular signaling proteins, receptor proteins and effector proteins

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12
Q

What features do protein kinases have?

A

They transfer a phosphate group onto proteins, they can be phosphorylated themselves, they oppose the desphosphorylating activity of phosphatases, they control numerous cellular processes and are very abudant in the genome and they can integrate information from several pathways

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13
Q

What is a polysome?

A

A complex of many ribosomes that simultaneously translate a single mRNA

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14
Q

what is a major advantage of using green fluorescent protein in cell biology?

A

It allows the observation of protein and organelles in living cells

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15
Q

Describe nuclear lamina of animal cells

A

It contains nuclear lamina, it helps the cell to organise the nucleus and it disassembles during mitosis

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16
Q

what does the nucleus contain?

A

Heterochromatin, euchromatin and nucleolus

17
Q

What is endocytosis

A

the process of uptake of material into the cell

18
Q

How do organelles of the endomembrane system communicate with each other?

A

Transporting vesicles

19
Q

What does the sER support?

A

synthesis of lipids

20
Q

Describe the Golgi apparatus

A

It consists of membrane sacks

21
Q

What pH is the interior of a lysosome kept at?

A

pH 5

22
Q

What does the endosomal compartment consist of?

A

early, recycling and late endosomes

23
Q

What are lipid droplets

A

fat storage compartments that are generated at the sER

24
Q

What does fusion of transport vesicles with a target membrane involve?

A

tethering of the vesicle to factors in the target membrane and docking of the vesicle to the target membrane

25
Q

What vesicles are released into the extracellular space by fusion of endoscopes with plasma membrane?

A

Exosomes

26
Q

Describe actin polymerisation

A

tightly controlled by cofilin, thymosin and profilin

27
Q

What cellular tasks does the cytoskeleton have?

A

It connects all parts of the cell, it supports motility and helps spatial organisation of cell

28
Q

What roles do microtubule plus end binding proteins have?

A

control of microtubule dynamics and mediating interactions with the plasma membrane

29
Q

What function do intermediate filaments have?

A

Mechanical support to resist forces

30
Q

Describe dynein

A

a microtubule minus end directed motor complex