Vimentin Flashcards
1
Q
What components does vimentin stain?
A
Mesenchymal
(cells that develop into connective tissue, blood vessels, and lymphatic tissue)
2
Q
Why is vimentin almost always present in tissue sections?
A
Because of its presence in background stromal elements
3
Q
Vimentin positivity is a marker for which type of cancer?
A
Mesenchymally derived tumors
- sarcoma
- melanoma
- lymphoma/leukemia
- seminomas
- neural tumors
4
Q
Absence of staining for vimentin can be used as a marker for to exclude which type of cancer?
A
Melanoma
Schwannoma
These two are always positive for vimentin
5
Q
What type of staining does vimentin present?
A
Cytoplasmic staining
