Video 6 Pulmonary Blood Flow Flashcards
What is pulmonary blood flow
Means by which oxygenated blood moves from the periphery to the body
diff between pulmonary and systemic circulations (3)
- Mean pressure is higher in systemic circulation
- The systemic circulation has muscular arterioles that constrict and increase in diameter
- VR on the systemic side is 10x that of pulmonary side
Pressure in left atrium
5 mmHg
vascular resistance =
delta P/flow
What causes compression of capillaries?
Increased pressure in alveolar pressure
Is this a pulmonary artery or vein?
It is a vein; It is not next to an airway
Is the pressure around pulmonary veins Same as alveolar pressure?
No, the alveolar walls are under tension and pulling on the walls of the pulmonary vein, therefore the pressure is lower than alveolar pressure
What is the difference between alveolar and extra-alveolar vessels?
alveolar vessels are mainly capillaries exposed to alveolar pressure; Extra-alveolar vessels are not exposed to alveolar pressure, contain some smooth muscle and have a tendency to get smaller
What is this chart depecting
Increased arterial OR venous pressure decreases pulmonary VR
What are the effects of increased capillary pressure? (2)
- Recruitment
- Distension
What is recruitment?
capillaries open up and allow flow
what is distension?
increase in width/size of the capillaries
Blood flow near the base of the lung is _______ and increases/decreases? as we go up the lung
high
decreases
T/F: Pulmonary blood flow is affected by posture
true
3 nongravitational causes of uneven blood flow
- Random variations in resistance of blood vessels
- Proximal regions of acinus receive more blood flow than distal
- Some regions of the lung have higher VR
What is hypoxic pulmonary vasoconstriction
When the pulmonary VR greatly increases due to decreased concentrations of inspired oxygen
Where is ACE found in the lungs?
Surface of the endothelial cells
Examples of biological inactivation in the lungs
- Bradykinin
- Serotonin
- Prostaglandins
- NE (partially)
What substance is secreted by the lungs?
Immunoglobulins