Video 3 Blood Gas transport

Question 1

What is the partial pressure of oxygen? How do you calculate it?

Answer 1

160 mmHg
0.21 (concentration of oxygen) x 760 mmHg (barometric pressure)

Question 2

When air is inspired it is _______ and _______ and saturated with _________ at _______ degrees celcius.

Answer 2

warmed
moistened
water vapor
37

Question 3

What is the partial pressure of water vapor at 37 degrees?

Answer 3

47 mmHg

Question 4

What needs to be considered when calculating the partial pressure of oxygen? How is it calculated?

Answer 4

The inspired gas is moist, subtract the partial pressure of water vapor from the barometric pressure before multiplying by 0.21
760-47= 713 mmHg
0.21 x 713 mmHg= 150 mmHg

Question 5

What is the partial pressure of oxygen in water if equilibrated to oxygen in air?

Answer 5

150 mmHg

Question 6

What is the concentration of oxygen in air vs water? Why such a difference?

Answer 6

21 ml/dl vs 0.45 ml/dl
The solubility of oxygen in water is very low

Question 7

PO2 in arterial blood

Answer 7

100 mmHg

Question 8

Amount of oxygen dissolved in arterial blood

Answer 8

0.3 ml/dl OR 3ml/liter

Question 9

Why isnt oxygen in solution sufficient for our tissues?

Answer 9

oxygen in transport (hemoglobin) is required because the maximum O2 available in solution is 90 ml/min assuming a cardiac output of 30 liters/min during exercise. The O2 requirement at that level is 3000 ml/min

Question 10

Structure of hemoglobin

Answer 10

4 heme molecules, 4 polypeptide chains (2 alpha and 2 beta)

Question 11

Hemoglobin A vs hemoglobin F

Answer 11

adult vs fetal

Question 12

Fetal Hb has a high ______

Answer 12

oxygen affinity

Question 13

Describe sickle cell hemoglobin

Answer 13

one chain is altered due to mutation