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Microbiology - Gram Negative > Vibrio > Flashcards

Vibrio Flashcards

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Biology 101 flashcards
1
Q

What is the main disease it causes?

A

Cholera

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2
Q

What is the host?

A

Only man

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3
Q

Which type of Vibrio causes cholera?

A

Only V.cholerae with CT (cholera toxin)

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4
Q

What do the non-cholera vibrios include?

A

V.cholerae without CT and all other Vibrios

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5
Q

How does V.cholerae spread?

A

Water and raw seafood
Spreads via F&B contaminated with human faeces

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6
Q

What does V.cholerae cause?

A

Enteritis, diarrhoea

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7
Q

Where is V.parahemolyticus found in?

A

Fresh and seawater, raw seafood

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8
Q

What does V.parahemolyticus cause?

A

Gastroenteritis and SSTI
Food poisoning - diarrhoea and vomiting usually within 24hours (acute onset of explosive watery diarrhea or frank dysentry-like syndrome)
*self-limiting
*

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9
Q

Where is V.vulnificus found in?

A

Raw seafood, oysters, seawater

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10
Q

What does V.vulnificus cause?

A

SSTI - wound infection, fasciitis, septicaemia in immunocompromised

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11
Q

How to treat V.vulnificus?

A
  • Aggressive surgical wound Debridement
  • Combination: doxy/ceftazidime/cipro
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12
Q

What is used to plate V.cholerae and how does it look like?

A

Curved gram negative rods and yellow on Thiosulphate Citrate Bile salts and sucrose

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13
Q

What are the different types of cholera toxin V.cholerae?

A

-Type O1: 98% of epidemic cholera
-Type O139: 2% of epidemic cholera

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14
Q

How is cholera toxin spread?

A

Bacteriophage

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15
Q

What kind of diarrhoea does V. cholerae cause?

A

Rice water stool, copious watery painless diarrhoea

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16
Q

How common is vomiting in V.cholerae?

A

Moderately common

17
Q

Is there fever and abdominal pain in V.cholerae?

A

Uncommon

18
Q

What are the virulence factors of V.cholerae? How do they work?

A

“A” unit causes diarrhoeal disease
-inhibits Na+ and HCO3- uptake and causes hypersecretion of Cl- and HCO3-, with enormous water loss

“B” unit binds and is immunogenic

19
Q

What is the vaccine given for V.cholerae?

A

Oral inactivated V.cholerae 01 + toxin B subunit

20
Q

What can be done with Cholerae? Aka how to treat?

A

Rehydration with electrolytes
Ciprofloxacin, tetracycline

Microbiology - Gram Negative (25 decks)

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