Via Clássica da Apoptose Flashcards

1
Q

Via Clássica - Vias de Ativação 2

A

Via Intrínseca

Via Extrínseca

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2
Q

Via Intrínseca - Início

A

Citoplasma → organela → mitocôndria

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3
Q

Via Intrínseca - Ativação

A

Ativada por alguns fatores.

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4
Q

Via Intrínseca - Fatores 3

A

Stress Oxidativo

Lesão no DNA

Hormônios

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5
Q

​Lesão no DNA → ?

Hormônios → ?

A

​Lesão no DNA → radiação / fármacos quimioterápicos

Hormônios → corticosteroides

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6
Q

Via Extrínseca - Início

A

Estimulantes externos à célula.

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7
Q

Via Extrínseca - Estímulo

A

Estimulam receptores da morte / Death Receptors

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8
Q

Via Extrínseca - Estímulo → Exemplos de situações aonde vamos ter o estímulo desses receptores: 2

A

Citosinas

Micro-organismos

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