Vessel Diseases

Question 1

thromboembolic disease

Answer 1

• organizing fibrin clots in pulmonary arteries

- may be in situ (thrombus) or travel to the lung from elsewhere (embolism)

Question 2

Talc embolism

Answer 2

• polarized crystals around vessels
• may include foreign-body multinucleated giant cells
• usually from IV drugs
• talc particles light under polarized light

Question 3

Pulmonary hypertension

Answer 3

• muscular hypertrophy of pulmonary arteries
• muscularization of arterioles (which should not have muscles)
• some forms may have plexiform lesions (artery lumen replaced by endothelial proliferation with numerous tangled slit-like lumens

Question 4

vasculitis

Answer 4

• inflammation in vesssel wall
• often with alveolar hemorrhage
• may be autoimmune or infection