Vesicular Disease - Luby

Question 1

transmission of FMD transmits via

Answer 1

aerosols (100 km)
animal contact
fomites:
humans

Question 2

HOw long can cattle be carriers of FMD?

Answer 2

2 years.

Question 3

FMD etiology

Answer 3

picornavirus

Question 4

FMD virus is inactivated by

Answer 4

high or low pH
sunlight
high temps
most disinfectants

Question 5

what is FMD not inactivated by?

Answer 5

pasteurization

Question 6

Pathophysiology of FMD

Answer 6

pharyu/intestinal mucosa/alveolar epi in udder v–> spread locally –> circulation –> target tissues (cporonary band, mouth, rumen, myocardial, skeletal muscle)–> vesicle formation –> 48 horus later, rupture –> mucosal sloughing and erosion.

Question 7

Clinical signs of FMD

Answer 7

Salvation
fever, depression, anorexia
lip smacking
nasal discharge
lameness
**** vesicle formation (0.5cm-10) which rupture at 48 hours

Question 8

Target tissues of FMD

Answer 8

cporonary band, mouth, rumen, myocardial, skeletal muscle, mammary tissue

Question 9

Differentials for vesicles

Answer 9

vesicular stomatits
bovine papular stomaitis
bluetongue
rinderpest
MCF
Severe IBR
Bovine herpes mamilitis
ingestion of irritant substances

Question 10

IF you suspect FMD:

Answer 10

immediately call the CFIA (we probly wont have to do the
Do NOT leave the farm or permit anyone to leave
never hesitate calling CFIA about potentials

Question 11

Bluetongue etiology

Answer 11

arthropod-borne viral disease of domestic and wild ruminants. SPecifically culicoides

Question 12

Bluetongue replicates hwere

Answer 12

in the insects and arthropods

Question 13

Transmissino of Bluetongue

Answer 13

placenta

semen

Question 14

pathophysiology of Bluetongue

Answer 14

infected –> virus hits vascular epithelium –> vasculitis –> edema of mucosal/epithelial surfaces. If exposed before, the disease gts worse

Question 15

Bluetongue Clinical signs

Answer 15

fever
edema of face lips, muzzle and ears
excessive salivation
oral erosions and so on
petechial
lameness, coronitis, sloughing of hooves.
abortions and birth defect. (important to dx abortions)

Question 16

Bluetongue Dx

Answer 16

??? figure this one out

Question 17

Vesicular stomatitis where is it?

Answer 17

only western hemisphere

in Mexico and south america

Question 18

Vesicular stomatitis strains that are important

Answer 18

New JErsey strain: most common and virulent

Indiana strain: less common and virulent

Question 19

Vesicular stomatitis can’t really be distinguished from

Answer 19

FMD

Question 20

pathogenesis of VSV

Answer 20

viremia –> locallization of virus in mm of mouth, skin around mouth and coronary bands (30% of lesions are vesicles) - the rest of lesions just seep and leave areas of necrosis

Question 21

Vesicular stomatitis clinical signs in cattle

Answer 21

fever, salivation, anorexia
vesicles of tongue, dental pads, lips, buccal mucosa, coronary band
necrotic lesions may be present

Question 22

Vesicular stomatitis clinical signs in horses

Answer 22

similar to cattle
short period of disease
LAMENESS *****

Question 23

Vesicular stomatitis clinical signs in pigs

Answer 23

vesicles on or behind the snout on the feet.

LAMENESS ***

Question 24

What are the federally reportable diseases and what do you do if you see them?

Answer 24

FMD, Vesicular Disease, Bluetongue.

Even if we suspect them, we need to call.