VENTILATION, GAS EXCHANGE AND PH HOMEOSTASIS PART 3 Flashcards
WHAT IS THE HENDERSON- HASSELBALCH EQUATION?
This equation makes a link beween ph and how its affected by the carbonate ion and co2 concenrtaion.
PH=Pka + log 10( hco3-/co2)
what are the repiratory causes of change in ph?
hypoventilation and hyperventlation.
what are the metabolic changes that cause a change in ph.
Diabetic Ketoacidosis (acidosis) Renal Failure (acidosis) Vomiting= alkalosis (bile salts increase in cavities )
whats respiratory acidosis caused by?
respiratory acidosis is caused by the lungs reatining co2 and it can be caused in people with copd, pneumonia.
what are the symproms of respiratory acidosis?
Reduction in Blood pressure
Dizziness
Drowsiness
Disoreintation
how dos the body respond to repiratory acidosis?
kidney compensates by
increasing plasma carbonate ions and extracting H+ ions in urine
this takes long 3-5 days
carbonate ions increases, ph rises until its restored.
but the partical pressure of carbon dioxide and hco3- are still high.
body response to respiratory alkalosis?
The bodys response to respirtory alkalosis is:
kidneys respond by increasing H+ ions in the Plasma and excreting more carbonate ions into urine.
what are the names of the chemoreceptors used to detect changes in blood ph?
peripheral chemoreceptors
central chemoreceptors
what are the two types of peripheral chemoreceptors?
The two peripheral chemoreceptors are the aortic and carotid bodies.
what do arotic bodies detect?
the aortic bodies detect changes in carbon dioxide and oxygen levels. more so oxygen levels.
what do the central chemoreceptors detect?
the central chemoreceptors detect changes in carbon diocide only via the blood brain barrier.
what do the carotid bodies detect?
C ia the 3 letter of the alphabet
the carotid bodies detect changes in carbon dioxide, ph and oxygen levels
