Ventilation and lung volume, gas transport... L5 Flashcards

1
Q

ventilation=

A

movement of air into and out of the lungs

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2
Q

minute volume

A

volume of ai entering and leaving the lungs each minute

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3
Q

tidal volume

A

the volume of each breath

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4
Q

vital capacity (VC)

A

the volume of maximum expiration following maximum inspiration

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5
Q

how to calculate minute volume

A

respiratory rate x tidal volume

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6
Q

residual volume=

A

the air remaining in the lungs after a maximal expiration

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7
Q

why is alveolar ventilation less than pulmonary ventilation

A

because of dead space

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8
Q

how can be measure ventilation

A

spirometry

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9
Q

2 things that cannot be measured by spirometry

A

residual volume and functional residual capacity

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10
Q

what illness causes increased Residual volume

A

emphysema

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11
Q

FEV1=

A

forced expiratory volume in 1 second

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12
Q

what can be expressed as a percentage with FEV1

A

FEV1/ FVC (forced vital capacity)

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13
Q

PEFR=

A

peak expiratory flow rate

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14
Q

how to measure airway obstruction?

A

PEFR

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15
Q

what is the driving force of O2 into lungs and CO2 out

A

pressure gradient

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16
Q

Measure of O2 in the blood (bound to Hb and dissolved)

A

CaO2

17
Q

Measure of O2 bound to Hb

A

SaO2

18
Q

3 ways CO2 is carried in the blood

A

Dissolved
As HCO3- (70%)
As carbamino compounds

19
Q

what is the formation of HCO3- increases by

A

carbonic anhydrase

20
Q

where is carbonic anhydrase not present

A

plasma

21
Q

structure of adult haemoglobin

A

2 alpha

2 beta chains

22
Q

what shifts the O2 dissocation curve to the right

A

increased CO2
increase temp
increase BPG
Increased H+

23
Q

what shifts the O2 dissocation curve to the left

A

decreased body temp
decreases CO2
increased pH
foetal Hb

24
Q

what does hyperventilation cause

A
low CO2 (hypocapnia) 
and alkalosis
25
Q

what does hypoventilation cause

A

high CO2 (hypercapnia) and acidosis

26
Q

diabetic ketoacidosis–>

A

acidosis

27
Q

renal failure–>

A

acidosis

28
Q

Vomiting–>

A

alkalosis

29
Q

dead space=

A

volume of lung not avalible for gas exchange

30
Q

anatomical dead space

A

due to normal non- exchanging parts of airways (nasopharynx, trachea ect)

31
Q

normal dead space

A

150ml

32
Q

physiological dead space

A

volume of alveoli that receive air but insufficient blood supply