Venous thrombosis - Anti-thrombotic therapy + Diagnosis, prevention and treatment of PE/DVT Flashcards
What is the normal bleeding time?
1-9 minutes
how is arterial trhombosis treated
- asprin and other antuplatelets
- reperfusion (catheter directed treatments + stents)
- thrombolytric therapy (streptokinase tissue plasminogen activator)
why is Fondaparinux favoured over heparin
Importance Fondaparinux was associated with reduced major bleeding events and improved survival compared with low-molecular-weight heparin (LMWH)
where do DVT’s most commonly occur
peripherally - ileofemoral and popliteal
what test would you do suspecting DVT
D dimer blood test and imaging
sensitive but no specific
what are the components of virchows triad
- realated to blood intravascular vessel wall damage, stasis of flow, and the presence of a hypercoagulable state
what are venous thrombosis treatments
- LMWH
- Warfarin
- DOAC
- endovacular treatment (catheter treatment in vein)
- surgery
what does haparin bind to
antithrombin
what is HIT and which heparin is it more commone with
- Heparin‐induced thrombocytopenia
- UFH (unfractionated heparin )
what clotting factors do DOAC’s work on
factor 2 or 10
when are doac’s not used
when patients have metalic heart valves
what are the symptoms oF DVT
Leg pain, swellin
what are the signs of DVT
tenderness, swelling, warmth, discolouration
what are the complications of DVT
Phlegmasia Alba Dolens and Phlegmasia Cerulae Dolens, PE (pulm embo)
what are the symptoms of pulmanory embolism
brealthlessness, pleuretic pain, symptoms of DVT
