Venous disorders and vascular neoplasms Flashcards

1
Q

Complications of varicose veins

A

Stasis dermatitis
Ulcerations
Poor wound healing
Superimposed infections
Rupture, leading to hemorrhage

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2
Q

Complication of a neoplasm that results in marked dilation of the veins of the head, neck and arms with cyanosis and respiratory distress

A

SVC syndrome

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3
Q

Sign of renal involvement in IVC syndrome

A

Massive proteinuria

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4
Q

Ectasia type characterized by a flat, light pink to deep purple lesion on the head/neck. Spontaneously regresses. Blanches when compressed. Symmetric. Commonly called a birthmark.

A

Nevus simplex

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5
Q

Ectasia type characterized that grows during childhood and does not fade/regress with time. Associated with Sturge Weber syndrome. Pink lesion of the face, not symmetric.

A

Nevus flammeus

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6
Q

Ectasia type characterized by lesions of the face, neck and upper chest. Radial, pulsatile arrays of dilated subcutaneous arteries/arterioles about a central core. Blanch with pressure. Associated with hyperestrogenic states.

A

Spider telangiectasias

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7
Q

Ectasia type characterized by dilated capillaries and veins over respiratory, GI, and urinary tract membranes that spontaneously rupture. Lesions seen in the mouth, lips, and around the fingernails.

A

Hereditary hemorrhagic telangiectasia (Osler-Wever-Rendu disease)

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8
Q

Hemangioma type characterized by thin-walled capillaries with scant stroma, increased frequency with age, and it does not regress.

A

Capillary (cherry) hemangioma

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9
Q

Hemangioma type that is seen in newborns that grows initially and will completely regress by age 7.

A

Juvenile (strawberry) hemangioma

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10
Q

Hemangioma type that is more infiltrative and frequently involves deep structure. It does not spontaneously regress. It is characterized by infiltrative border, unencapsulated, and is composed of large, cavernous blood filled vascular spaces separated by CT stroma. Associated with VHL disease

A

Cavernous hemangiomas

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11
Q

Hemangioma characterized by red pedunculated lesions on the skin and gingival/oral mucosa. Easily bleed and ulcerate.

A

Pyogenic granulomas

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12
Q

Lymphangioma type that predominantly effects the head, neck, and axillary subcutaneous tissues. Characterized by networks of endothelium-lined spaces that can be distinguished from capillary channels only by the absence of RBCs.

A

Simple/capillary lymphangiomas

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13
Q

Lymphangioma type that effects the neck, axilla, or retroperitoneum. Characterized by indistinct margins, unencapsulated, massively dilated lymphatic spaces, and separated by intervening CT stroma containing lymphoid aggregates

A

Cavernous lymphangiomas –> also called cystic hygromas or Turner syndrome

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14
Q

Benign, reddish-blue nodule arising from modified smooth muscle cells. Seen in the distal portion of digits, particularly under the nail.

A

Glomus tumor

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15
Q

Vascular proliferation in immunocompromised hosts characterized by red papules and nodules, and rounded subcutaneous masses.

A

Bacillary angiomatosis

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16
Q

Infectious organism associated with bacillary angiomatosis

A

Gram negative bacilli of Bartonella family (B henselae and B quintana)

17
Q

Microscopy of red papule shows capillary proliferation with prominent epitheloid endothelial cells exhibiting nuclear atypia and mitoses.

A

Bacillary angiomatosis

18
Q

Caused by HHV8 and closely associated with AIDs

A

Kaposi sarcoma

19
Q

3 progression stages of Kaposi sarcoma

A

Red-purple macules, typically in LE
Raised plaques
Nodular

20
Q

Microscopy shows proliferating spindle cells forming slit-like spaces filled with blood. Mitoses, extravasated RBCs, and hemosiderin is common.

A

Kaposi sarcoma

21
Q

Malignant endothelial neoplasms seen in skin, soft tissue, breasts, and liver. Seen in older adults.

A

Angiosarcoma

22
Q

Carcinogens associated with hepatic angiosarcoma.

A

Arsenic
Thorotrast
Polyvinyl chloride

23
Q

Microscopy shows plump, atypical endothelial cells forming vascular channels. Wildly undifferentiated tumors with a solid spindled appearance and no discernible blood vessels.

A

Angiosarcoma