Vecuronium/ Norcuron Flashcards
0
Q
Mech of action
A
Nicotinic ACh R-antagonist > competes with ACh at neuromuscular junction and prevents binding thus inhibiting skeletal muscle depolarization
1
Q
Class
A
Non-depolarizing neuromuscular blocker
2
Q
Phamakokinetics
A
Onset- <1minute
Peak- 3-5 minutes
Duration- 30-80 minutes
HL- 30-80 minutes
3
Q
Indications
A
Need for temporary paralysis to facilitate endotracheal intubation
Need for continued paralysis following endotracheal intubation
4
Q
Contraindicatons
A
Hypersensitivity
5
Q
Side effects
A
Bradycardia, hypotension
6
Q
Dose
A
Adult- 0.08-0.1 mg/kg IV, IO
Pedi- 0.1 mg/kg IV, IO
7
Q
Precautions
A
Presence of neuromuscular diseases may be associated with prolonged paralysis
8
Q
Drug - Drug
A
Potentiated by lidocaine, procainamide, B blockers, mag sulfate, and other neuromuscular blockers
