Etomidate/ Amidate Flashcards

0
Q

Mech of action

A

Depresses reticular activating system of the brain and potentiates GABA > causes sedation

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1
Q

Class

A

Sedative/ Hypnotic

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2
Q

Pharmakokinetics

A

Onset- 10-20 seconds
Peak- <1minute
Duration- 3-5 minutes
HL- 30-70 minutes

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3
Q

Indications

A

Induction agent for RSI

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4
Q

Contraindications

A

Hypersensitivity

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5
Q

Side effects

A

Myoclonic skeletal muscle movement, apnea, hyperventilation, hypoventilation, laryngospasm, HTN, hypotension, tachycardia, bradycardia, NV

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6
Q

Dose

A

Adult- 0.3mg/kg IV, IO over 15-30 seconds

Pedi- same

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7
Q

Precautions

A

Consider alternate sedative in patients with severe asthma

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8
Q

Drug - Drug

A

May prolong respiratory depression and apnea with Verapamil

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