Vasopressor Continuous Infusion

Question 1

Vasopressor Continuous Infusion - Epinephrine

Answer 1

• Mix: inject 1 mg epinephrine into 1000 mL Normal Saline bag to achieve 1mcg/mL concentration (This means 1 mL of 1:1000 or 10 mL of 1:10,000 – either way 1 mg of drug). Use macro drip set.
• Adult IV/IO: Begin IV/IO infusion wide open to gravity to give small aliquots of fluid. Typical volumes are less than 100 mL of total fluid, as typical doses are expected to be < 100 mcg. Titrate to desired hemodynamic effect with goal BP of > 90 mmHg systolic, improved respiratory status (bronchodilation), and improved perfusion/mentation

Question 2

Vasopressor Continuous Infusion - Dopamine

Answer 2

• Mix: 400 mg in 250 ml NS or 800 mg in 500 ml NS to produce concentration of 1600 mcg/mL
• Adult IV/IO: 5-20 mcg/kg/min, start at 5 mcg/kg/min, Titrate dose up 5 mcg/kg/min every 5 min to a max of 20 mcg/kg/min to desired hemodynamic effect.