Vasopressin

Question 1

Vasopressin (Pitressin synthetic)

Class

Answer 1

Antidiuretic hormone

Question 2

Vasopressin (Pitressin synthetic)

Mechanism of Actions

Answer 2

Stimulation of V1 smooth muscle receptors, potent vasoconstriction when given in high doses.

Question 3

Vasopressin (Pitressin synthetic)

Indications

Answer 3

Alternate vasopressor to the first or second dose of epinephrine in cardiac arrest, may be useful in cases of vasodilatory shock, i.e. sepsis

Question 4

Vasopressin (Pitressin synthetic)

Contraindications

Answer 4

Responsive Patients with coronary artery disease

Question 5

Vasopressin (Pitressin synthetic)

Adverse Reactions

Answer 5

Bronchoconstriction, ischemic chest pain, nausea, vomiting,

abdominal pain.

Question 6

Vasopressin (Pitressin synthetic)

Drug Interactions

Answer 6

None

Question 7

Vasopressin (Pitressin synthetic)

Adult Dosage

Answer 7

40-unit one time dose to replace the first or second dose of epinephrine in cardiac arrest.

Question 8

Vasopressin (Pitressin synthetic)

Pediatric Dosage

Answer 8

Not Recommended

Question 9

Vasopressin (Pitressin synthetic)

Onset

Answer 9

Immediate

Question 10

Vasopressin (Pitressin synthetic)

Duration

Answer 10

Variable

Question 11

Vasopressin (Pitressin synthetic)

Special Considerations

Answer 11

May increase peripheral vascular resistance and provoke cardiac ischemia and angina