Racemic Epinephrine

Question 1

Epinephrine Racemic (Micronefrin, Vaponefrin)
Class

Answer 1

Sympathomimetic

Question 2

Epinephrine Racemic (Micronefrin, Vaponefrin)
Mechanism of Actions

Answer 2

Useful in treating laryngeal edema; inhibits histamine release.

Question 3

Epinephrine Racemic (Micronefrin, Vaponefrin)
Indicatons

Answer 3

Croup, laryngotracheobronchitis, laryngeal edema

Question 4

Epinephrine Racemic (Micronefrin, Vaponefrin)
Contraindications

Answer 4

Hypertension, underlying cardiovascular disease, and epiglotitis

Question 5

Epinephrine Racemic (Micronefrin, Vaponefrin)
Adverse Reactions

Answer 5

Tachycardia, arrhythmias

Question 6

Epinephrine Racemic (Micronefrin, Vaponefrin)
Drug Interactions

Answer 6

MAOIs and bretylum may potentiate the effects, beta blockers may block the effects

Question 7

Epinephrine Racemic (Micronefrin, Vaponefrin)
Adult Dosage

Answer 7

Solution – 0.25-0.75 ml of 2.2% solution in 2.0 ml NS

Question 8

Epinephrine Racemic (Micronefrin, Vaponefrin)
Pediatric Dosage
Under 20kg

Answer 8

Solution: < 20 kg dilute 0.25 mL in 2.5 mL of NS.

Question 9

Epinephrine Racemic (Micronefrin, Vaponefrin)
Pediatric Dosage
20kg to 40 kg

Answer 9

Dilute 0.5 mL in 2.5 mL of NS.

Question 10

Epinephrine Racemic (Micronefrin, Vaponefrin)
Pediatric Dosage
> 40 kg

Answer 10

Dilute .75 mL in 2.5 mL of NS. Administer via aerosolization.

Question 11

Epinephrine Racemic (Micronefrin, Vaponefrin)
Onset

Answer 11

Within 5 minutes

Question 12

Epinephrine Racemic (Micronefrin, Vaponefrin)
Peak Effect

Answer 12

5-15 minutes

Question 13

Epinephrine Racemic (Micronefrin, Vaponefrin)
Duration

Answer 13

1-3 Hours

Question 14

Epinephrine Racemic (Micronefrin, Vaponefrin)
Special Considerations

Answer 14

May cause tachycardia and arrhythmias; monitor vital signs; excessive amounts may cause bronchoconstriction.