Epinephrine Flashcards
Epinephrine 1:1,000
Adrenalin
Class
Sympathomimetic
Epinephrine 1:1,000
Adrenalin
Mechanism of Action
Bronchial Dilation; Direct-acting alpha- and beta-agonist.
Epinephrine 1:1,000
Adrenalin
Indications
Allergic reactions, anaphylaxis, and bronchial asthma. Symptomatic bradycardia where patient is not responsive to other interventions.
Epinephrine 1:1,000
Adrenalin
Adverse Reactions
Hypertension, tachycardia, arrhythmias, pulmonary edema, anxiety, restlessness, psychomotor agitation, nausea, headache, and angina.
Epinephrine 1:1,000
Adrenalin
Drug Interactions
Potentiates other sympathomimetics
deactivated by alkaline solutions, (i.e. Sodium bicarbonate)
monoamine oxidase inhibitors (MAOIs) may potentiate effects
beta-blockers may blunt effects.
Epinephrine 1:1,000
Adrenalin
Adult Dose
Allergic Reaction
- 3 – 0.5 mg 1:1,000 IM/SC
0. 1 - 0.3 mg IV.
Epinephrine 1:1,000
Adrenalin
Continuous Infusion for Bradycardia
Add 1 mg (1 mL of 1:1,000 solution) to 500 mL of NS or D5W. Initial infusion rate of 1 mcg/min titrated to effect (typical dose 2 – 10 mcg/min).
Epinephrine 1:1,000
Adrenalin
Profound Bradycardia or Hypotension
2 – 10 mcg/min; titrate to patient response.
Epinephrine 1:1,000
Adrenalin
Pediatric
0.01 mg/kg up to 0.3 mg
Epinephrine 1:1000
Adrenalin
Contraindication or Relative Contraindication
Hypothermia
Contraindication
Epinephrine 1:1000
Adrenalin
Contraindication or Relative Contraindication
Tacharrhythmia
Contraindication
Epinephrine 1:1000
Adrenalin
Contraindication or Relative Contraindication
Pulmonary Edema
Contraindication
Epinephrine 1:1000
Adrenalin
Contraindication or Relative Contraindication
Myocardial Ischemia
Contraindication
Epinephrine 1:1000
Adrenalin
Contraindication or Relative Contraindication
Hypovolemic Shock
Contraindication
Epinephrine 1:1000
Adrenalin
Contraindication or Relative Contraindication
Underlying Cardiovascular DIsease/ Angina
Relative Contraindication