Vasodilators and treatment of angina Flashcards

1
Q

MoA of sildenafil (viagra)

A

Inhibits phosphodiesterase-5, enhancing effects of nitric oxide-activated increases in cGMP

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2
Q

MoA of nitrates

A

Relax vascular smooth muscle, at low doses dilates veins and at high doses dilates arterioles

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