Antimicrobials

Question 1

MoA of fluoroquiunones

Answer 1

Inhibit DNA gyrase (topoisomerase II) and topoisomerase IV

Question 2

Drug used for MRSA

Answer 2

Vancomycin

Question 3

Vancomycin MoA

Answer 3

Binds D-Ala-D-Ala on murein monomers and prevents polymerization of the murein monomers

Question 4

Meningitis prophylaxis in exposed patients

Answer 4

Rifampin

Question 5

Technique used to diagnose perianal itching, and the drug used to treat it

Answer 5

Scotch tape method, and mebendazole

Question 6

MoA of sulfonamides

Answer 6

Inhibit dihydropteroate synthase

Question 7

Cheap wide spectrum antibiotic DOC of otitis media

Answer 7

Amoxicillin

Question 8

Drug of choice for Tx. of pseudomembranous colitis

Answer 8

Metronidazole

Question 9

Anemia caused by trimethoprim

Answer 9

Megaloblastic anemia

Question 10

DOC for giardia, bacterial vaginosis, pseudomembranous colitis, and trichomonas

Answer 10

Metronidazole

Question 11

Treatment for TB patients (think RIPE)

Answer 11

Rifampin, Isoniazid, Pyrazinamide, and Ethambutol

Question 12

Common side effect of rifampin

Answer 12

Orange urine discoloration

Question 13

DOC for influenza A and B

Answer 13

Oseltamivir or Zanamivir

Question 14

DOC for RSV

Answer 14

Ribavirin

Question 15

HIV antiviral class known to have severe drug interactions by causing inhibition of metabolism

Answer 15

Protease inhibitors

Question 16

DOC for N. gonorrheae

Answer 16

Ceftriaxone

Question 17

DOC for herpes and its MoA

Answer 17

Acyclovir; activates thymidine kinase

Question 18

Anti-bacterials that cause hemolysis in G6-PD-eficient patients

Answer 18

Sulfonamides