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Year2 MSK exam2 > Vasculitis part I > Flashcards

Vasculitis part I Flashcards

1
Q

What causes vasculitis

A

IC and actiation of C’

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2
Q

what do you see in vasculitis vessel

A

damage to walls
leukocytoclastic changes
necrosis and thrombosis

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3
Q

clinical Sx of vasculitis is determined how

A

vessel size

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4
Q

what are the constitutional Sx in vasculitis

A

fever, weight loss, malaise

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5
Q

what are the large vessel vasculitis clinical manifestations

A 
limb claudication
asymmetric BP
absence of pulses
bruits
aortic dilation
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6
Q

clinical manifestations of medium vessel vasculitis

A 
ulcers
arthritis
livedo reticularis
digital gangrene
Mononeuritis multiplex!!
microaneurysms
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7
Q

clinical manifestations of small vessel vasculitis

A 
purpura
urticaria
glomerulonephritis
alveolar hemorrhage
arthritis
splinter hemorrhages
uveitus
episcleritis
scleritis
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8
Q

behcets

A

vessel vasculitis of any size

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9
Q

What are the large vessel vasculitis

A

takayasu arteritis

giant cell arteritis

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10
Q

what are the medium vessel vasculitis

A

polyarteritis nodosa

kawasaki disease

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11
Q

what are the small vessel vasculitis

A

ANA assoc

IC associated

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12
Q

What are the ANCA related small vessel vasculitis

A

microscopic polyangiitis
granulomatosis with polyangiitis(wegener)
eosinophilic granulomatosis with polyangiitis (churg strauss)

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13
Q

What are the IC related small vessel vasculitis

A

Ant GBM
cryoglobulinemic vasculitis
IgA HSP
hypocomplemetemic urticarial vasculitis

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14
Q

what are the variable vessel vasculitis

A

behcets

cogans IgG4 related

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15
Q

what are the single organ vasculitis

A

cutaneous vasculitis

primary CNS vasculitis “string of beads”

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16
Q

most common presentation of vasculitis syndrome

A

palpable purpura

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17
Q

what causes inflammatroy palpable purpura

A

leukocytoclastic vasculitis

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18
Q

what is used for Tx remission vasculitis

A

glycocorticoids and cyclophosphamides

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19
Q

maintenance of vasculitis

A

AZA or MTX or mycophenolate

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20
Q

what is temporal arteritis

A

granulomatous giant cell arteritis

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21
Q

takayasu arteritis race

A

asian

22
Q

BP different in R arm compared to L

A

large arter vasculitis

23
Q

2 phases of takayasu arteritis

A

early inflammatory and late occlusive

24
Q

bruit heard where in takayasu

A

subclavian or aorta

25
Q

what is pulseless disease and Tx

A

takayasu arteritis

Tx steroids

26
Q

jaw claudication or pain with chewing

A

temporal arteritis

27
Q

stenosis wehre with temporal arteritis

A

subclavian stenosis or aneurysm

28
Q

Sed rate is extremely high

A

temporal arteritis

29
Q

fever of unknown origin

A

temporal arteritis

30
Q

What can termporal arteritis look like

A

polymyalgia theumatica

31
Q

main signs temporal arteritis or giant cell

A 
>50 y.o
Feve unkown origin
paraneoplastic
jaw claudication
proximal pain and stiffness
elevated ESR
inc alk phos
32
Q 
left wrist drop and right foot drop
fever arthralgias HTN hematuria
testicular tenderness
hep B +
med size vesslaneurysms
A

polyarteritis nodosum

33
Q

signs polyarteritis nodosum

A

][livedo reticularis

foot drop or polyneuropathy

34
Q

Sx polyarteritis nodosum

A 
HTN
fever weight loss
abdominal pain
lungs spared
testicular pain or tenderness
myalgias
35
Q

labs for polyarteritis nodosa

A

azotemia, anemia
Hep B virus
Bx skin nerve muscle or testicles
angiogram renal, mesenteric hepatic artery

36
Q

med vessel aneurysms

A

polyarteritis nodosa

37
Q

child with fever for 5 days
erythema and edema palms soles
cervical adenopathy

A

Kawasaki syndrome

38
Q

concerned about what in kawasaki disease

A

coronary artery aneurysm

39
Q

kawasaki disease criteria

A

needs fever >5 days
4/5 of the following:
- conjunctivitis
- rash: erythematous, maculopapular, mobiliform
-erythema palms and soles
-adenopathy, cervical
- mucous membrane dry red strawberry tongue

40
Q

lab to order in kawasaki disease

A

echo to make sure heart is okay

41
Q

SLE patient with wheals that don’t go away followed by echymosis
C’ levels low

A

urticarial vasculitis

42
Q

what is the Anti C1q vasculitis

A

hypocomplemetemic urticarial vasculitis

43
Q

what produce urticaria ain urticarial vasculitis

A

C3a and C5a

44
Q

what cause urticarial vasculitis

A

CT diseases

hep B or C

45
Q

what causes hypocomplementemic form urticarial vasculitis

A

SLE with Ab to Cq1 and vascular endothelial cells

46
Q 
18 y.o with fever palpable skin lesions arthralgias
hematuria
abdominal pain
GI bleeding
Ig involved
A

IgA

47
Q

Sx with HSP

A

purpura
arthritis
GI abdominal pain with bleeding

48
Q

what is the single organ IgA disease

A

beurgers

49
Q

typical UA finding in HSP

A

RBC cast in urine

50
Q

sat on cold bleacher and caused necrotizing vasculitis

A

mixed cryoglobulinemia

51
Q

what to eval patient for with mixed cryoglobulinemia

A

hep C

Year2 MSK exam2 (17 decks)

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