Vasculitis

Question 1

Define vasculitis.

Answer 1

Inflammation and necrosis of blood vessels

Question 2

How are vasculitides classified?

Answer 2

According to the size of the vessel affecred

Question 3

Name two of each of the following:

a) large vessel vasculitis
b) medium
c) small

Answer 3

a) giant cell arteritis, Takayasu’s aortitis
b) Polyarteritis nodosa, Kawasaki’s disease
c) Wegener’s granulomatosis, microscopic polyangiitis

Question 4

How are the small vessel vasculitides further classified?

Answer 4

ANCA +ve and -ve

Question 5

How do the large and small/medium vasculitides differ in presentation?

Answer 5

Large- classical clinical pattern based on vessel affected

Medium/small- multiorgan involvement with less specific features

Question 6

Name the vasculitis being described:

a) jaw claudication, scalp tenderness, visual loss
b) microaneurysms, thrombosis, infarctions, hypertension, testicular pain
c) nasal discharge, ulceration, haemoptysis, sinusitis, glomerulonephritis

Answer 6

a) GCA/temporal arteritis
b) polyarteritis nodosa
c) Wegener’s granulomatosis