Sjogren's syndrome Flashcards
1
Q
What is Sjogren’s syndrome?
A
Chronic autoimmune inflammatory disorder characterised by lymphocytic infiltration of exocrine glands
2
Q
What is the difference between primary and secondary Sjogren’s?
A
Primary- develops in isolation
Secondary- develops along with other autoimmune phenomena (such as RA, SLE, scleroderma)
3
Q
How does Sjogren’s present?
A
Dry mouth and dry eyes Vaginal dryness 20% have Raynaud's Dysphagia Recurrent sinusitis Dry cough
4
Q
What tests are carried out when investigating a possible diagnosis of Sjogren’s syndrome?
A
Schirmer’s test
Gland biopsy
Autoantibodies- ANA, rheumatoid factor, Ro/La
5
Q
How is Sjogren’s managed?
A
Saliva replacement
Eye drops
Vaginal lubricants
Pilocarpine
6
Q
What are the possible complications of Sjogren’s?
A
Lymphoma
Extraglandular disease
Congenital heart block (disease in pregnancy)
