Passmedicine Flashcards
What should patients who are already taking allopurinol do during an acute attack?
Continue taking allopurinol
What should be first-line treatment in osteoarthritis?
Oral paracetamol (+ topical NSAID if knee/wrist)
What initial management should be given to newly diagnosed patients with RA?
MTX + sulfasalazine + short course prednisolone
What is a common side-effect of colchicine?
Diarrhoea
What are the first-line treatments in ankylosing spondylitis?
NSAIDs along with exercise programme
What does raised ALP in old man with bone pain suggest?
Paget’s disease
What should be co-prescribed with an NSAID in OA patients?
PPI
What are the cut-offs for a) osteopenia and b) osteoporosis in a DEXA scan?
a) <-2.5
A defect in which gene causes Marfan’s syndrome?
Fibrillin-1
In patients taking methotrexate, what drug should be avoided?
Trimethoprim- increased chance of haematological toxicity
Calcification of the articular cartilage in a painful swollen knee points to which diagnosis?
Pseudogout
How should anti-phospholipid syndrome be treated in pregnancy?
Low dose aspirin and low dose LMWH
Which diagnosis is suggested by systemic upset and unequal pressure in the upper limbs?
Takayasu’s arteritis, a large vessel vasculitis
Which cardiac problems are patients with ankylosing spondylitis prone to developing?
Aortic regurgitation
AV node block
What can be said about CK level in polymyalgia rheumatica?
Usually normal
