Vasculitis (3)

Question 1

What is it?

How is it classified?

Answer 1

➊ Inflammation of blood vessels

➋ • Small Vessel - Henoch-Schoenlein Purpura, Microscopic Polyangiitis, Granulomatosis with polyangiitis
• Medium Vessel - Kawasaki Disease, Polyarteritis Nodosa
• Large Vessel - GCA, Takayasu’s Arteritis

Question 2

What are the features of it?

Answer 2

• Purpura - non-blanching spots from blood leaking out of vessels under the skin
• Arthralgia, Myalgia
• Peripheral neuropathy
• Diarrhoea, Abdominal pain
• Anterior uveitis and scleritis
• HTN

Question 3

Which bloods should be done?

How is it managed?

Answer 3

➊ • ESR, CRP - Raised
• ANCA - +ve in many cases

➋ Steroids + Immunosuppressants