Vascular Tumors

Question 1

Exposure to which substances is associated with angiosarcomas

Answer 1

polyvinyl choloride

arsenic

Thorotrast

Question 2

Exposure to polyvinyl chloride, arsenic, or Thorotrast is associated with which tumor?

Answer 2

angiosarcoma

Question 3

What is “blanching”?

Answer 3

lesion turns which when pressed on

ability to push blood out of lesion

• hemangiomas: blanch b/c made of blood vessels*
• angiosarcomas: non-blanching (endothelial cells)*
• Kaposi sarcoma: non-blanchin (endothelial cells)*

Question 4

What disease and virus is Kaposi sarcoma assocated with?

Answer 4

HIV/AIDS

Kaposi caused by HHV-8

Question 5

Presentation/timing of hemangioma

Answer 5

usually present at birth

blanching benign tumor of blood vessels

Question 6

What type of proliferation causes hemangiomas?

Answer 6

blood vessel tumor

Question 7

What type of tissue proliferates to cause angiosarcoma?

Answer 7

endothelial tissue

Question 8

What type of tissue proliferates to cause a Kaposi sarcoma?

Answer 8

endothelial tissue

Question 9

Which organs are angiosarcomas usually found in?

Answer 9

skin, breat, liver

Question 10

Morphology of Kaposi sarcoma

Answer 10

purple patches, plaques, nodules

Question 11

Populations normally affected my Kaposi sarcoma

Answer 11

AIDS patients

old Eastern European males

transplant recipients (back off on immunosuppression)

Question 12

How to you treat Kaposi sarcoma in transplant (immunosuppressed) patients

Answer 12

back off a little on immunosuppression