Vascular Pathology

Question 1

what is vascular pathology?

Answer 1

Obstruction or occlusion leads to ischemia → which causes cell death

Question 2

what is the most common cause of obstruction of blood vessels

Answer 2

arteriosclerosis

Question 3

what is arteriosclerosis

Answer 3

Narrowing (or hardening) of the arteries caused by a thickening of the artery wall → the result is a stiff artery with decreased capacity to move blood through the body

Question 4

atherosclerosis is a type of arteriosclerosis T or F

Answer 4

T

Question 5

what is the pathogenesis of atherosclerosis?

Answer 5

build up of plaque in medium vessels causing intramural thickening of arterial lumen
- chronic endothelial cell injury and inflammation due to hyperlipidemia, HTN, toxins

Question 6

what contributes to plaque in atherosclerosis

Answer 6

Low density lipoproteins (LDLs) accumulating in blood vessels

Question 7

what do endothelial cells do

Answer 7

regulate vasodilation and vasoconstriction, promote hemostasis and prevent thrombosis