Vascular path

Question 1

MCC autoamputation in smokers

Answer 1

Uber germ disease / thromboangitis obliterans

Question 2

String of pearl app in pt w Hx HBV ?

Answer 2

Polyarteritis nodosa

• renal microaneurysm

Question 3

Mediterranean/ Turkish pt w Hx HSV or Parvovirus is at risk of developing what ?

Answer 3

Beçhet syndrome

• rec apthous ulcer, genital ulcers, uveitis, erythema nodosum

HLA B51

Question 4

MCC necrotizing granulomatous in luck and kidney seen w?

Answer 4

1. Granulomatousis w polyangitis (Wegner)
   - cANCA / anti-proteinase 3

Tx: cyclophosphamide, steroids

2. lung + kidney + skin : Microscopic polyangitis
   - pANCA / anti-myeloperoxidase

Question 5

Peripheral neuropathy w Hx HCV seen in?

Answer 5

Mixed cryoglobulinemia

• ppt in cold
• IgG + IgM deposition