Valve Disease Flashcards

1
Q

Atherogenic and genetic factors

A

Athero - inc BMP2, dec OPG, inc MMP

Genetic - NOTCH 1 mutation

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2
Q

Effects of aortic stensosi

A
LVH (concentric)
LHF
Secondary mitral insuff
Inc LA pressure
Afib and thrombus in LAA
Bivent failure
Coronary insuff
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3
Q

BAV

A

Predisposes to dilation of ascending TAA due to intrinsic medial aortopathy

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4
Q

Acute RF

A

Childhood

Rise in ASO

Polarthritis with rash, nodules and chorea

Pancarditis

Aschoff bodies

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5
Q

Signs of carditis

A

Murmur, cardiac enlargement, CHF, pericarditis

Subq nodules at joints

Erythemia marginatum in acute RF

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6
Q

Dx of acute RF

A

Major - caridtis, polyarthritis, chorea, erthemia marginatum, subq nodeus

Minor - fever, arthralgia, inc ESR or CRP, prolonged PR

Dx need strep plus 2 major or 1 minor 1 major

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7
Q

Dx of IE

A

Majhor - 2 separate cultures, ECHO, new valve regurg

Minor - predisposing condition or drug use
Temp over 28C
Vascular phenomena
Immunological pheno
Microbiologic evidecne 

2 major, 1 minor and 3 major or 5 minor

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8
Q

Chronc RHD

A

Valve fibrosis and deformity

Stneosis and insuff

Mitral»>aortic»>tricuspind

Fishmouth orifice

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9
Q

MAC

A

Older women
ESRD with hypercalc
Asx leading to regurg or stenossi
Induces a LBBB

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10
Q

FMV

A
PVCs with palpitations
Midsystolic click
Progressive mitral regurg (late systolic)
Bact endocarditis
Sudden death
Most isolated
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11
Q

Ebstein’s malformation

A

Of tricuspid vlave

Right o left shunt across PFO

Fuindger clubbing due to hypoxia

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12
Q

Subtype of endocarditis

A

RHD - no orgs

IE - colonies of virulent and non virulent

NBTE - no orgas

LSE - from lupus

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13
Q

Comps of IE

A

Mycotic aneurysm in renal artery

Splenic abscess

SKin rash (Oslers nodes and Janeway lesions)

Fatal cerebral he,morrhage from rupture of mycotic aneurysm

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