Vaccines,Antibiotics,Clinical Trials Flashcards

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1
Q

About 200 years ago smallpox was a deadly disease. ___________ was a doctor in Gloucestershire. He noticed that people who caught cowpox were immune to ________. Cowpox is a mild disease which can be caught from cattle.

A

Edward Jenner

Smallpox

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2
Q

Jenner scratched the skin of a young boy. He the rubbed in _____from a person suffering from cowpox. The boy caught cowpox but soon recovered and was immune to the disease. Then he inoculated the boy with pus from a ______ victim. The boy did not catch the deadly smallpox. They had become _____ to smallpox because the virus had similar ______ to the cow pox virus.

A

Pus
Smallpox
Immune
Antigens

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3
Q

What is Poliomyelitis?

A

A virus that destroys nerve cells. It damages the spinal cord so much that victims become paralyzed.

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4
Q

Who made a vaccine for polio in 1953?

A

Jonas Salk

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5
Q

Jonas Salk was able to kill samples of polio. He injected the _____ ______ into people gave them immunity to the disease. Polio has now disappeared from developed countries.

A

Dead Virus

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6
Q

In 1999 which country became the first to use a vaccine against Meningitis C?

A

The UK

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7
Q

First used in Britain in 1998, the combined MMR vaccine gives protection against three diseases _____[3]. It was controversial because some people wrongly feared that the vaccine would make their children more susceptible to a condition called _______.

A

Autism

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8
Q

What is autism?

A

Mental condition impairing responses.

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9
Q

There are some diseases that vaccines can not be made for. If there is an______ of the disease people need protection quickly. They can be injected with _____-_____ antibodies. These antibodies have been made in the body of another person or animals.

A

Outbreak

Ready-Made

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10
Q

What is the problem with antibodies which have not been made by ourselves? And what else do we need?

A

It does not last very long. We need a further dose or booster. Boosters are needed to protect against typhoid and cholera.

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11
Q

How do antibiotics relieve symptoms?

A

By killing pathogens

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12
Q

Who discovered the first antibiotic in 1928?

A

Alexander Fleming

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13
Q

Alexander Fleming was growing bacteria on ______ plates. But he left one of the plates open by mistake. ______ started growing on the surface. He noticed that the mould was stopping the bacteria from growing. The mould was called _____________.

A

Agar
Mould
Penicillium Notatum

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14
Q

10 years later Howard Florey and Ernst Chain discovered how to extract large quantities of the active _______ found in mould. This substance was called ________ and was the first antibiotic. It was quickly put to good use in treating soldiers wounds in the _______ ________ ________.

A

Substance
Penicillin
Second World War

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15
Q

Today when we talk about penicillin we are referring to a large group of ________. These are produced by a variety of different strains of the penicillium ______.

A

Antibiotics

Fungus

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16
Q

What is a placebo?

A

An inactive substance that has no treatment value. In clinical trials experimental treatments are often compared with placebos to asses the treatment’s effectiveness.

17
Q

What is a blinded study?

A

A study where the participants do not know whether they being given the experimental treatment or a placebo.

18
Q

What is a double-blinded study?

A

A study where neither the participants nor the study staff know which patients are receiving the experimental treatment and which ones are receiving a placebo. These studies are performed so that neither the patients’ nor the doctors’ expectations about the experimental drug can influence the outcome.

19
Q

Some diseases can be treated with medicines that contain useful drugs. But before they can be used any medical treatment has to be extensively ______ and _____.

A

Tested and trialed

20
Q

What are clinical trials used for?

A

They are used to determine whether drugs and treatments are both safe and effective.

21
Q

When are new therapies tested on people?

A

After laboratory and animal studies show promising results.

22
Q

All clinical trials are based upon a set of rules called a ______.

A

Protocol

23
Q

What is a protocol?

A

A protocol sets out what types of people will participate in the trial, along with the schedule of tests,procedures,medications and dosages and the length of the study.

24
Q

In a clinical trial the participants are seen regularly by the research ______ who monitor their health and determine the safety and effectiveness of the treatment.

A

Staff