vaccines Flashcards by Korey koper

HBV Routine immunization of infants– 3 doses ?

Birth, 1 month, 6 months

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HBV Routine immunization for adolescents ?

3 doses of pediatric or

2 doses of adult

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Pediatric HBV ?

Recombivax or Engerix 0.5 ml IM

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Adult HBV ?

Recombivax 1 ml IM

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RV5 ?

Rotateq

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RV5 doses ?

latex-free, no reconstitution needed, 3 dose series

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RV1 ?

Rotarix

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RV1 doses ?

has latex, must be reconstituted with diluent, possible increase risk of intussusception, 2 dose series

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RV1 months ?

oral

2 and 4

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RV5 months ?

oral

2 4 6

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Rotavirus, dont start if ?

Do not start if 15 weeks or older

If infant spits it up, do not repeat dose

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DTaP marketed as ?

Daptacel, Infanrix, Tripedia

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DTaP amount ?

0.5 mL IM

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DTaP months ?

2, 4, 6 and 15-18 months, and 4-6 years (5 doses)

5 doses

3 months – not adequately immunized

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DT ?

when pertussis is contraindicated

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Td ?

tetanus toxoid and reduced amount of diphtheria, typically for adults requiring tetanus

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DtaP-Hib ?

(TriHIBit),

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DTaP-IPV-HepB ?

(Pedarix),

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DTaP-IPV-Hib ?

(Pentacel),

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DTaP-IPV ?

(Kinrix)

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DTaP contraindications ?

Anaphylactic-type reaction to previous dose

Encephalopathy within 7 days of previous dose (not attributable to another cause)

Progressive neurologic d/o

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DTaP precautions ?

High fever (40.5C)

Persistent, inconsolable crying within 48⁰ of previous dose

Seizures within 3 days of previous dose

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DTaP AR ?

Local reaction, especially with increasing number of doses

Fever

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PedvaxHIB months ?

2, 4, and 12-15 mos

H. flu only

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ActHIB months ?

2, 4, 6 and 12-15 mos H. fu only

Pneumococcal conjugate vaccine (PCV13) recommendation ?

all children younger than 5 years old, all adults 65 years or older, and people 6 years or older with certain risk factors.

Pneumococcal polysaccharide vaccine (PPSV23) recommendation ?

all adults 65 years or older. People 2 through 64 years old who are at high risk of pneumococcal disease should also receive PPSV23.

PCV13: Age at 1st dose (months): 2-6 months ?

3 doses 1 dose at 12-15 mos booster

PCV13: Age at 1st dose (months) 7-11 months ?

2 doses 1 dose at 12-15 mos booster

PCV13: Age at 1st dose (months) 12-23 months ?

2 doses no booster

PCV13: Age at 1st dose (months) 24-59 months in healthy children ?

1 dose no booster

PCV13: Age at 1st dose (months) 24-71 months in children at risk* ?

2 doses no booster

IPV route and months

Subcut 2, 4, and 6-18 mos and 4-6 years. ALL need a dose at 4-6 years

LAIV marketed as ?

Fluzone, Fluvirin, Fluarix, Afluria

Annual vaccination for ALL people 6 mos old and up, in the fall Each year a new formulation is made, based on surveillance in Asia ?

LAIV

LAIV Children 6-35 months dosing ?

0.25 mL IM, older children 0.5 mL

MMR given in two doses – months ?

12-15 mos and 4-6 yrs

MMRV higher rate of ?

seizures

Reconstitute with diluent, inject sub cut ?

MMR

Rule out pregnancy first and advise no conception for __ mos after injection for MMR

MMR contrindications ?

Pregnant, immunocompromised, egg allergy, high-dose steroids

MMR AR ?

Few develop fever 6-12 days later 5% get a rash Rare – encephalitis, Guillain- Barre (1 in 3 million) Febrile seizure, esp if MMRV

VAR marketed as ?

Varivax

VAR store in ?

freezer

VAR need to be reconstituted , T or F ?

VAR dosing schedule ?

12-15 mos and 4-6 years | May do MMRV for 2nd dose

VAR contraindications ?

Severe allergic reaction to previous dose Immunodeficient Pregnant women

VAR precaution ?

Personal or family hx of febrile seizures

VAR AR ?

20% get minor injection site reactions Rash

HepA for ?

children travelers to countries with high rates of Hep A children with Hep B or Hep C infection children with clotting disorders adolescent/adult males who have sex with men occupational exposure illegal drug users close contact with international adoptee 2-18 yo if previously unimmunized

HepA marketed as ?

Havrix or Vaqta

HepA doses and route ?

2 dose IM

HepA 1-18 years ?

0.5 mL, 6-18 mos apart

HepA 19+ years ?

1.0 mL, 6-18 mos apart

HepA contrindications ?

Allergic reaction to previous dose

HepA precautions ?

Pregnant Moderate/severe illness

HepA AR ?

Uncommon and mild – injection site pain, HA, loss of appetite

Meningococcal Vaccine serogroups ?

A, B, C, W-135 and Y

Meningococcal Vaccine serogroups that predominate in the US ?

B C Y

No vaccine for serogroup __ ?

Two MCV4 vaccines available – ?

Menactra and Menveo

MCV4 for who ?

For all people 11-12 years, booster dose at age 16 years Earlier and more frequent doses for those at risk

MCV4 dosing ?

0.5

Neisseria meningitidis who is at risk ?

College freshmen living in dorms Military recruits People who travel to or live in countries with high rates of meningococcal disease People with complement deficiency People with functional or anatomic asplenia Immunocompromised people so give them the MCV4 vaccine

MCV 4 contrindications ?

Allergic reaction to vaccine or diphtheria toxoid

MCV4 precautions ?

Okay to give to immunosuppressed patients

MCV4 AR ?

Injection site pain 4.3% get more systemic reactions – fever, HA, fatigue, malaise, arthralgias, vomiting, diarrhea, rash, seizures

Meningitis Exposure ?

Post-exposure prophylaxis for close contacts Within 24 hours Rifampin, ceftriaxone, maybe cipro

Tdap – marketed as ?

Boostrix, Adacel

Tdap 11-18 yo doses ?

0.5 mL IM INSTEAD OF the Td booster

Tdap 19-64 y.o. dosing ?

single dose of Tdap

Tdap 65+ yo. dosing ?

single dose of Tdap if not previously dosed and if will have contact with an infant

Tdap contrindications ?

allergy

Tdap precautions ?

Guillain-Barre within 6 wks of previous tetanus vaccine

Tdap AR ?

local pain, HA, fatigue

Most common STI in US ?

HPV

HPV: Types 16 and 18 cause 70% of ?

cervical cancers

HPV: Types 6 and 11 cause 90% of ?

genital warts

HPV dosing and months ?

3 doses, 0.5 mL IM 0, 2 and 6 months

HPV they can start when ?

Can start as early as 9 2 doses for 9-14 yo (6 months apart)

HPV recommendation ?

all 11- 12 yrs and through 26 yo if not previously immunized 3 doses

Other Vaccines ?

``` Rabies Vaccine Typhoid Fever Vaccine Japanese Encephalitis Vaccine Tuberculosis Vaccine Yellow Fever Vaccine ```