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1 STEP Uworld immunology > Vaccines > Flashcards

Vaccines Flashcards

1
Q

Adenovirus?

A

NON-ATTENUATED, given to military recruits

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2
Q

Typhoid? admin?

A

Ty21a, oral

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3
Q

Ty21a, oral?

A

Typhoid, live attenuated

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4
Q

Polio, Sabin?

A

live attenutated, ORAL

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5
Q

Varicella (chickenpox)?

A

live attenuated

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6
Q

Smallpox?

A

live attenuated

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7
Q

BCG?

A

live attenuated

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8
Q

Yellow fever?

A

live attenuated

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9
Q

Influenza, intranasal?

A

live attenuated

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10
Q

MMR?

A

live attenuated

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11
Q

Rotavirus?

A

live attenuated

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12
Q

Rabies?

A

killed/inactivated

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13
Q

Influenza injection?

A

killed/inactivated

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14
Q

polio, salk?

A

killed/inactivated

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15
Q

HAV?

A

killed/inactivated

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16
Q

typhoid, Vi polycacharide, intramuscular?

A

killed/inactivated

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17
Q

HBV(antigen HBsAg)?

A

Subunit

18
Q

HPV (6, 11, 16)?

A

Subunit

19
Q

acellular pertusis (aP)?

A

Subunit

20
Q

N. meningitidis?

A

Subunit

21
Q

S. pneumonia?

A

Subunit

22
Q

H. influenza B?

A

Subunit

23
Q

c. tetani?

A

toxoid

24
Q

C. diphteria?

A

toxoid

25
Q

m/os loses pathogenicity, but retains capacity for transient growth within inoculated host?

A

live attenuated

26
Q

live attenuated what systems response?

A

CELLULAR AND HUMORAL

27
Q

live attenuated contraindicated?

A

in pregnant and immunodeficiency, because can revert to virulent form

28
Q

MMR and varicella can be given to HIV without evidence of immunity if CD4 > 200

A

.

29
Q

Pathogen is inactivated by heat or chemicals. maintain epitope - important for immune response.?

A

killed/inactivated

30
Q

killed/inactivated - what response?

A

ONLY HUMORAL

31
Q

what induces strong, life long response?

A

live attenuated

32
Q

what is safer than live?

A

killed/inactivated

33
Q

cons of inactivated?

A

weaker immune response, booster shoots needed

34
Q

Include only antigens that best stimulaet the immune system?

A

subunit

35
Q

subunit pros?

A

lower chance of adverse reactions

36
Q

subunit cons?

A

expensive, weaker immune response

37
Q

denatured bacterial toxin with intact receptor binding?

A

toxoid

38
Q

stimulated immune response to make antibodies without potential for causing disease?

A

toxoid

39
Q

toxoid pros?

A

protects agains toxins

40
Q

toxoid cons?

A

antitoxin levels decrease with time, may require booster

1 STEP Uworld immunology (13 decks)

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