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1 STEP Uworld immunology > antibodies > Flashcards

antibodies Flashcards

1
Q

Anti-ACh receptor?

A

Myastenia gravis

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2
Q

Myastenia gravis

A

Anti-ACh receptor

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3
Q

Anti-presynaptic voltage-gated calcium channel?

A

Lamber-Eaton myastenic syndrome

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4
Q

Lamber-Eaton myastenic syndrome

A

Anti-presynaptic voltage-gated calcium channel

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5
Q

Anti-beta2 glycoprotein I?

A

Antiphospholipid syndrome

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6
Q

Antiphospholipid syndrome

A

Anti-beta2 glycoprotein I

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7
Q

Antinuclear (ANA)?

A

nonspecific screening antibody, often associated with SLE (high sensitivity, low specificity)

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8
Q

nonspecific screening antibody, often associated with SLE (high sensitivity, low specificity)

A

Antinuclear (ANA)

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9
Q

Anticardiolipin, lupus anticoagulant?

A

SLE, antiphospholipid syndrome

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10
Q

SLE, antiphospholipid syndrome

A

Anticardiolipin, lupus anticoagulant

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11
Q

Anti-dsDNA, anti-Smith?

A

SLE (highly specific, low sensitivity)

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12
Q

SLE (highly specific, low sensitivity)

A

Anti-dsDNA, anti-Smith

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13
Q

Anti-histone?

A

Drug-induced lupus

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14
Q

Drug-induced lupus

A

Anti-histone

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15
Q

Anti-U1 RNP (ribonucleoprotein)?

A

Mixed connective tissue disease

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16
Q

Mixed connective tissue disease

A

Anti-U1 RNP (ribonucleoprotein)

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17
Q

Rheumatoid factor (IgM antibody against IgG Fc region)?

A

RA

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18
Q

RA

A

Rheumatoid factor (IgM antibody against IgG Fc region)

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19
Q

Anti-CCP (more specific)?

A

RA (dar vienas)

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20
Q

RA (dar vienas)

A

Anti-CCP (more specific)

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21
Q

Anti-Ro/SSA, Anti-La/SSB?

A

Sjogren syndrome

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22
Q

Sjogren syndrome

A

Anti-Ro/SSA, Anti-La/SSB

23
Q

Anti-Scl-70 (anti-DNA topoisomerase I)?

A

Scleroderma (diffuse)

24
Q

Scleroderma (diffuse)

A

Anti-Scl-70 (anti-DNA topoisomerase I)

25
Q

Anticentromere?

A

Limited scleroderma (CREST syndrome)

26
Q

Limited scleroderma (CREST syndrome)

A

Anticentromere

27
Q

Antisynthetase (eg. anti-Jo-1), anti-SRP, anti-helicase (anti-Mi-2)?

A

Polymyositis, dermatomyositis

28
Q

Polymyositis, dermatomyositis

A

Antisynthetase (eg. anti-Jo-1), anti-SRP, anti-helicase (anti-Mi-2)

29
Q

Antimitochondrial?

A

1* biliary cholangitis (Autoimmune disease)

30
Q

1* biliary cholangitis (Autoimmune disease)

A

Antimitochondrial

31
Q

Anti-smooth muscle?

A

Autoimmune hepatitis type 1

32
Q

Autoimmune hepatitis type 1

A

Anti-smooth muscle

33
Q

MPO-ANCA/p-ANCA?

A

Microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg-strauss syndrome), ulcerative colitis

34
Q

Microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg-strauss syndrome), ulcerative colitis

A

MPO-ANCA/p-ANCA

35
Q

PR3-ANCA/c-ANCA?

A

Granulomatosis with polyangiitis (Wegener)

36
Q

Granulomatosis with polyangiitis (Wegener)

A

PR3-ANCA/c-ANCA

37
Q

Antiphospholipase A2 receptor?

A

1* membranous nephropathy

38
Q

1* membranous nephropathy

A

Antiphospholipase A2 receptor

39
Q

Anti-hemidesmosome?

A

Bullous phemigoid

40
Q

Bullous phemigoid

A

Anti-hemidesmosome

41
Q

Anti-desmoglein (anti-desmosome)?

A

Pemphigus vulgaris

42
Q

Pemphigus vulgaris

A

Anti-desmoglein (anti-desmosome)

43
Q

Antimicrosomal, antithyroglobulin, antithyroid peroxidase?

A

Hashimoto thyroiditis

44
Q

Hashimoto thyroiditis

A

Antimicrosomal, antithyroglobulin, antithyroid peroxidase

45
Q

Anti-TSH receptor?

A

Graves disease

46
Q

Graves disease

A

Anti-TSH receptor

47
Q

IgA anti-endomysial, IgA anti-tissue transglutaminase, IgA and IgG deamidated gliadin peptide

A

Celiac disease

48
Q

Celiac disease

A

IgA anti-endomysial, IgA anti-tissue transglutaminase, IgA and IgG deamidated gliadin peptide

49
Q

Anti-glutamic acid decarboxylase, islet cell cytoplasmic antibodies?

A

Type I diabetes mellitus

50
Q

Type I diabetes mellitus

A

Anti-glutamic acid decarboxylase, islet cell cytoplasmic antibodies

51
Q

Antiparietal cell, anti-intrinsic factor?

A

Pernicious anemia

52
Q

Pernicious anemia

A

Antiparietal cell, anti-intrinsic factor

53
Q

Anti-glomerular basement membrane?

A

Goodpasture syndrome

54
Q

Goodpasture syndrome

A

Anti-glomerular basement membrane

1 STEP Uworld immunology (13 decks)

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