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1 STEP Uworld immunology > antibodies > Flashcards

antibodies Flashcards

1
Q

Anti-ACh receptor?

A

Myastenia gravis

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2
Q

Myastenia gravis

A

Anti-ACh receptor

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3
Q

Anti-presynaptic voltage-gated calcium channel?

A

Lamber-Eaton myastenic syndrome

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4
Q

Lamber-Eaton myastenic syndrome

A

Anti-presynaptic voltage-gated calcium channel

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5
Q

Anti-beta2 glycoprotein I?

A

Antiphospholipid syndrome

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6
Q

Antiphospholipid syndrome

A

Anti-beta2 glycoprotein I

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7
Q

Antinuclear (ANA)?

A

nonspecific screening antibody, often associated with SLE (high sensitivity, low specificity)

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8
Q

nonspecific screening antibody, often associated with SLE (high sensitivity, low specificity)

A

Antinuclear (ANA)

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9
Q

Anticardiolipin, lupus anticoagulant?

A

SLE, antiphospholipid syndrome

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10
Q

SLE, antiphospholipid syndrome

A

Anticardiolipin, lupus anticoagulant

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11
Q

Anti-dsDNA, anti-Smith?

A

SLE (highly specific, low sensitivity)

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12
Q

SLE (highly specific, low sensitivity)

A

Anti-dsDNA, anti-Smith

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13
Q

Anti-histone?

A

Drug-induced lupus

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14
Q

Drug-induced lupus

A

Anti-histone

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15
Q

Anti-U1 RNP (ribonucleoprotein)?

A

Mixed connective tissue disease

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16
Q

Mixed connective tissue disease

A

Anti-U1 RNP (ribonucleoprotein)

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17
Q

Rheumatoid factor (IgM antibody against IgG Fc region)?

A

RA

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18
Q

RA

A

Rheumatoid factor (IgM antibody against IgG Fc region)

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19
Q

Anti-CCP (more specific)?

A

RA (dar vienas)

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20
Q

RA (dar vienas)

A

Anti-CCP (more specific)

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21
Q

Anti-Ro/SSA, Anti-La/SSB?

A

Sjogren syndrome

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22
Q

Sjogren syndrome

A

Anti-Ro/SSA, Anti-La/SSB

23
Q

Anti-Scl-70 (anti-DNA topoisomerase I)?

A

Scleroderma (diffuse)

24
Q

Scleroderma (diffuse)

A

Anti-Scl-70 (anti-DNA topoisomerase I)

25
Anticentromere?
Limited scleroderma (CREST syndrome)
26
Limited scleroderma (CREST syndrome)
Anticentromere
27
Antisynthetase (eg. anti-Jo-1), anti-SRP, anti-helicase (anti-Mi-2)?
Polymyositis, dermatomyositis
28
Polymyositis, dermatomyositis
Antisynthetase (eg. anti-Jo-1), anti-SRP, anti-helicase (anti-Mi-2)
29
Antimitochondrial?
1* biliary cholangitis (Autoimmune disease)
30
1* biliary cholangitis (Autoimmune disease)
Antimitochondrial
31
Anti-smooth muscle?
Autoimmune hepatitis type 1
32
Autoimmune hepatitis type 1
Anti-smooth muscle
33
MPO-ANCA/p-ANCA?
Microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg-strauss syndrome), ulcerative colitis
34
Microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg-strauss syndrome), ulcerative colitis
MPO-ANCA/p-ANCA
35
PR3-ANCA/c-ANCA?
Granulomatosis with polyangiitis (Wegener)
36
Granulomatosis with polyangiitis (Wegener)
PR3-ANCA/c-ANCA
37
Antiphospholipase A2 receptor?
1* membranous nephropathy
38
1* membranous nephropathy
Antiphospholipase A2 receptor
39
Anti-hemidesmosome?
Bullous phemigoid
40
Bullous phemigoid
Anti-hemidesmosome
41
Anti-desmoglein (anti-desmosome)?
Pemphigus vulgaris
42
Pemphigus vulgaris
Anti-desmoglein (anti-desmosome)
43
Antimicrosomal, antithyroglobulin, antithyroid peroxidase?
Hashimoto thyroiditis
44
Hashimoto thyroiditis
Antimicrosomal, antithyroglobulin, antithyroid peroxidase
45
Anti-TSH receptor?
Graves disease
46
Graves disease
Anti-TSH receptor
47
IgA anti-endomysial, IgA anti-tissue transglutaminase, IgA and IgG deamidated gliadin peptide
Celiac disease
48
Celiac disease
IgA anti-endomysial, IgA anti-tissue transglutaminase, IgA and IgG deamidated gliadin peptide
49
Anti-glutamic acid decarboxylase, islet cell cytoplasmic antibodies?
Type I diabetes mellitus
50
Type I diabetes mellitus
Anti-glutamic acid decarboxylase, islet cell cytoplasmic antibodies
51
Antiparietal cell, anti-intrinsic factor?
Pernicious anemia
52
Pernicious anemia
Antiparietal cell, anti-intrinsic factor
53
Anti-glomerular basement membrane?
Goodpasture syndrome
54
Goodpasture syndrome
Anti-glomerular basement membrane

1 STEP Uworld immunology (13 decks)

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