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vaccines 1&2 Flashcards

1
Q

Enhance a specific immune response in an animal by exposing it to
vaccination

A

immunoprophylaxis

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2
Q

provides immediate protection, works for agents that are poor immunogens or where there are no vaccinations

A

passive immunoprophylaxis

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3
Q

which is strong/longer protection? active or passive immunoprophylaxis

A

active

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4
Q

indicates a successful induction of an immune response

A

immunization

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5
Q

T/F

all vaccines provide immunization

A

false

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6
Q

administration of an antigenic product

A

vaccination

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7
Q

____ is important for persistent intracellular or latent infection

A

cell mediated immunity

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8
Q

where do live vaccines replicate

A

in the host

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9
Q

which route of administration gives the greatest systemic immune response

A

subcutaneous

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10
Q

this route of administration stimulates a local IgA immune response

A

intranasal

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11
Q

T/F

killed vaccines replicate in the host

A

false they do not

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12
Q

T/F

non-infectious killed vaccines are stable and do not pose a risk to getting sick

A

TRUE

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13
Q

T/F

The immune response to killed vaccines is generally a shorter duration and narrower spectrum

A

true

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14
Q

purified subunit vaccines

A

Contain an immunogenic component of an infectious agent

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15
Q

In vitro production of large quantities of immunogenic proteins through genetic engineering specific antigens into bacteria, yeasts or cell lines

A

genetically engineered subunit protein vaccine

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16
Q

two reasons adjuvants are added

A

to increase
• Immunostimulation
• Duration of immunity

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17
Q

how do adjuvants work

A
  • Prolong antigen exposure
  • Enhance antigen presentation
  • Increase cytokine and immune response
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18
Q

T/F

Adjuvants have been implicated as causing granulomatous reactions at vaccine sites

A

TRUE – sarcomas in cats with FeLV using aluminum

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19
Q

what vaccines currently have transdermal use

A

Current used in FeLV in cats and canine melanoma vaccine

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20
Q

mucosal application vaccines

A

Currently used in Canine and feline respiratory infections (intranasal), FeCoV

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21
Q

Vaccines for kittens and puppies end at ??

A

16 weeks of age – boosters given at 6 months to a year after completion

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22
Q

T/F

vaccines protect 100% of the population

A

FALSE

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23
Q

immediate hypersensitivity reaction

24
Q

involves IgE mediated release of histamine

A

hypersensitivity type 1

25
which hypersensitivity reaction causes Angioedema and allergic rhinoconjunctivitis
type 1
26
Involves IgG or IgM antibodies bound to cell surface antigens with subsequent complement fixation
hypersensitivity type 2
27
which hypersensitivity reaction causes host cell hemolysis leading to hemolytic anemia
cytotoxic hypersensitivity reaction
28
what hypersensitivity reaction might inactivated rabies vaccine cause
type 1
29
The MLV of parvovirus could potentially cause this hypersensitivity reaction
type 2 - cytotoxic
30
Involved circulating antigen-antibody complexes that deposit in post capillary venules, with subsequent complement fixation
type 3 hypersensitivty reaction -- also called serum sickness
31
Dogs receiving the CAV-1 or less likely the CAV-2 vaccine can develop immune-complexes in the eye and result in_____
anterior uveitis -- this is type 3 hypersensitivity
32
vaccine reaction mediated by T cells not antibodies
delayed hypersensitivity reaction -- type 4
33
type 4 delayed hypersensitivity reaction is not common but can be seen when ___ is used as an immunostimulant compoung
BCG
34
breed predisposed to Polyradiculoneuritis
coon hounds
35
causes LMN 1-2 weeks post vaccination
Polyradiculoneuritis
36
Polyradiculoneuritis is from a specific rabies vax derived from what
suckling mouse brains
37
Most viruses are grown in cell cultures that contain serum from??
bovine fetuses
38
ischemic dermatopathy vax rxn
Widespread cutaneous vasculitis – ulceration, crusting, hyperpigmentation and alopecia associated with rabies 1-5 months post vaccination
39
adjuvants in FeLV that causes injection site sarcomas in cats
aluminum incidence of 1 in 10 000 vaccinated cats
40
Encephalomyelitis from the MLV of what
rabies
41
T/F | CPV or FPV vaccines are not to be given to pregnant females or animals < 4 weeks of age
true
42
Sudden onset of lameness between 3 and 15 days post vaccination
polyarthritis in dogs
43
Vaccine associated hypertrophic osteodystrophy and juvenile cellulitis is especially noted in what breed
weimaraners
44
Immune-mediated polyarthritis in young akitas occurs how many days post MLV
3-29 days | *clinical signs start at around 16 weeks
45
what is used for treatment in Immune-mediated polyarthritis in young akitas
corticosteroids can help with the inflammation but these dogs are usually euthanized by age 2 due to the progression and poor quality of life
46
what is a core vaccine
All dogs and cats, regardless of geographical location or circumstance • Protect against life threatening disease
47
vaccines Only required in specific geographical locations, local environments or lifestyle places
non-core vaccine
48
how often should vaccines be given to puppy or kitten and until when
start at 6-8 weeks old and give them every 2-4 weeks until 16 weeks old
49
T/F | If the dog is > 16 weeks then a single vaccination is sufficient
true
50
3 core vaccines for cats
FPV, FHV-1, FCV
51
which vaccines are carried out annually in high risk cats
FHV-1 and FCV
52
core vaccines in dogs
CDV, CPV-2, CAV | and rabies
53
T/F | vaccinate all cats for FeLV
false - only vaccinate negative cats
54
T/F | Chlamydophila and bordetella require tri-annual vaccinations
FALSE -- annual
55
Adjuvanted FeLV and rabies vaccination has been associated with ____
FISS
56
where do we give the FeLV vax
left leg
57
where do we give the rabies vax
right leg

small animal medicine (6 decks)

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