Vaccine Flashcards
1
Q
4 pros of mRNA vaccines
A
Gives immunity before pathogen exposure
Effective for vulnerable populations
Faster to develop
Robust induction of antibodies and T cell activation
2
Q
4 cons of mRNA vaccines
A
Short protection duration
Can potentiate chronic inflammatory responses
Loss of efficacy due to mutations
Adverse effects
3
Q
Example of short protection duration of mRNA vaccines
A
COVID vaccine only gives 6 months protection
4
Q
Example of mRNA vaccination efficacy loss due to mutation
A
COVID 19 Spike 51 protein mutated
5
Q
Example of robust induction of immunity from mRNA vaccine
A
Fast induction of IgM and IgG from COVID vaccine
Also CD4 and 8 induction