Vaccinations Flashcards
1
Q
What are the main aims of vaccinations?
A
Prevent morbidity/death from preventable diseases
2
Q
Name 4 examples of live vaccinations
A
BCG
Varicella
MMR
Yellow fever
3
Q
Name 3 examples of inactivated organism vaccines
A
Typhoid
Pertussis
IPV
4
Q
Name 2 inactivated toxin vaccines
A
Tetanus
Diphtheria
5
Q
Name 2 organism component vaccines
A
Influenza
Pneumococcal
6
Q
Advantages of live vaccines
A
- Single dose sufficient to induce long term immunity
- strong immune response evoked
7
Q
Disadvantages of live vaccines
A
- can become virulent
- possible contamination
- contraindicated in immunosuppressed
- Interference by viruses/vaccines/passive antibodies
- poor stability
8
Q
Advantages of attenuated/inactive vaccines
A
- Stable
- Unable to cause infection
9
Q
Disadvantages of Attenuated/inactive vaccines
A
- Not as long term (shorter term)
- Not as powerful immunity evoked - multiple doses required
