Vaccination Flashcards

1
Q

Infantile colic
3شروط
Prevalence

A

• Crying for no apparent reason that lasts
for ≥3 hours per day and occurs on ≥3
days per week in an otherwise healthy
infant <3 months of age. • Prevalence of colic in infants range
from 8 to 40 percent. • The incidence does not differ by
gender or the type of feeding.

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2
Q

Infantile colic

Etiology

A

Etiology is not known but some
possible explanation: • feeding techniques: overfeeding,
underfeeding or inadequate burping. • Cow’s milk protein intolerance but
usually has other symptoms. • Lactose intolerance. • Gastrointestinal immaturity:
incomplete absorption of
carbohydrates. • Intestinal hypermotility • Parental variables: anxiety of the
parents are transmitted to the child.

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3
Q

Injuries prevention

A

Children should be seated in the
rear seat of a vehicle until they are
13 years of age.

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4
Q

Baby Walkers

A

American Academy of Pediatrics
and The Canadian Pediatric
Society called for complete ban of
baby walkers.

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5
Q

Pa cifier Use

A
Pacifier use help soothing the child
and may decrease risk of SIDS. • It should not be discouraged in the
1st year of life but should be
restricted in children with
chronic/recurrent otitis media. • Pacifier should NOT be given
earlier than 3 to 4 weeks of age or
before breastfeeding has been
established
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6
Q

Sc reen Time

A
For children under 2 years
• old, screen time is not
recommended. • For children 2 to 5 years old,
limit  routine or regular screen
time to less than 1 hour per day.
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7
Q

Dental Care

A

Consider the first dentist visit by
6 months after eruption of 1st
tooth or at age 1 year then every
6 months.

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8
Q

Active immunization

A
Naturally can be acquired by
getting infected by the
organism/Vaccines are defined as whole or
parts of microorganisms
administered to prevent an
infectious disease.
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9
Q

Ty pes of vaccines

A
  1. Whole inactivated microorganisms (e.g., polio and hepatitis A) 2. Parts (subunits) of the organism (e.g., acellular pertussis, HPV, and hepatitis B). 3. Polysaccharide capsules conjugated to protein carriers (e.g., Haemophilus influenzae B, pneumococcal, and meningococcal conjugate vaccines).
  2. Live attenuated microorganisms (measles, mumps, rubella, varicella, rotavirus). 5.Toxoids (tetanus and diphtheria).
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10
Q

Diphtheria

A

• Caused by Corynebacterium diphtheriae • Incubation 2-5 days • Early – malaise, sore throat, difficulty in swallowing, loss of
appetite, hoarseness, mild fever • Within 2-3 days, adherent, gray membrane on oral mucous
membranes
– Extensive membrane - life-threatening airway obstruction. • Toxin – serious systemic complications including myocarditis • Death rate 5%-10%

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11
Q

TeTanus

A

• Spread by contact with soil
containing Clostridium tetani • Most infections from
contaminated wounds • Incubation 1-2 weeks • Not contagious • Produces exotoxin • Progressive muscle tightening,
descending pattern

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12
Q

Pe rtussis

A
• Caused by Bordetella pertussis
• Highly contagious
• 90% of household contacts
will acquire
• Starts as URI
• After 1-2 weeks – paroxysms of
severe coughing followed by
“whoop” with loud inspiration,
apnea and post tussive vomiting • Worse for very young
• Can lead to pneumonia, seizure
and encephalopathy
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13
Q

CI of DTaP

A
Severe allergic reaction (e.g.,
anaphylaxis) after a previous vaccine
dose – Encephalopathy (e.g., coma, decreased
level of consciousness; prolonged
seizures)
• not attributable to another
identifiable cause • within 7 days of administration of
previous dose of DTP or DTaP
clarified and stabilized
– Progressive neurologic disorder
• including infantile spasms
• uncontrolled epilepsy
• progressive encephalopathy – Defer DTaP until neurologic status
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14
Q

Polio

A

• Very infectious virus • Up to 95% of people infected with
polio have no symptoms • 4-8% minor symptoms – fatigue,
myalgias, stiffness • <1% have paralysis from virus
attacking motor neurons Polio Vaccine: • 2 types, Live attenuated (oral),
Inactivated (IPV). • Ideally all countries should switch to
IPV only.
• Trivalent OPV can cause Vaccine
Associated Paralytic Poliomyelitis
(VAPP) • Multiple doses series.

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15
Q

Hemophilus Influenza B(Hib)

A
Prior to vaccine, Hib was leading
cause of  childhood
– Bacterial meningitis – Epiglottitis
– Pneumonia – Empyema
– Pericarditis – Bacteremia • Hib vaccine available in
combination vaccine.
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16
Q

Streptococcus pneumoniae

A

– Common cause of community

acquired pneumonia and otitis media

17
Q

High risk children of pneumococcal disease PCV13

A
include
– Immunocompromised children
• HIV
• Chronic renal failure • Nephrotic syndrome • Lymphoma and leukemia • Chemotherapy
• Organ transplant
• Congenital
immunodeficiencies

High risk children include
– Immunocompetent children with
• Cyanotic congenital heart
defects • Chronic lung disease • Asthma needing oral steroid
treatment • Diabetes • CSF leaks • Cochlear implants • Asplenia (congenital or
acquired) • Sickle cell and other
hemoglobinopathies

18
Q

High risk children of pneumococcal disease PCV13

A
include
– Immunocompromised children
• HIV
• Chronic renal failure • Nephrotic syndrome • Lymphoma and leukemia • Chemotherapy
• Organ transplant
• Congenital
immunodeficiencies

High risk children include
– Immunocompetent children with
• Cyanotic congenital heart
defects • Chronic lung disease • Asthma needing oral steroid
treatment • Diabetes • CSF leaks • Cochlear implants • Asplenia (congenital or
acquired) • Sickle cell and other
hemoglobinopathies

19
Q

Rotavirus

A

Most common cause of
gastroenteritis worldwide • Can cause severe dehydration

Live attenuated rotavirus • Given orally on multiple doses • Narrow administration window
– First dose must be before 15
weeks – Last dose must be before 8
months

20
Q

Mumps

A

Fever, malaise, headache, myalgias • 48 hours later: parotitis (parotid gland
inflammation)

21
Q

Rubella

A

Rash and fever for 2-5 days • If acquired while pregnant, severe congenital defects
– Cataracts – Heart defects – Deafness – Mental retardation

22
Q

MMR

A

• Measles, Mumps, Rubella • Live attenuated vaccine • Given after 12 months old. • Not contraindicated in children with
egg allergy.

23
Q

Varicella Vaccine

A
Contraindications
– Severe allergic reaction (e.g.,
anaphylaxis) after previous dose
– Substantial suppression of
cellular immunity

Safe Situations to Administer Varicella Vaccine
• Immunodeficient family member
or household contact. • Asymptomatic or mildly
symptomatic HIV infection (CD4
count >200).

24
Q

Meningococcal vaccine

A

• All currently available vaccines
effective against Groups A, C, Y,
and W-135 • Meningococcal B vaccine is only
recommended to high risk
population for invasive
meningococcal disease such as
sickle cell anemia or asplenia. • Conjugated vaccines developed
– Produces memory cells – Preferred vaccine choice

25
Q

Vaccines contain Aluminum!

A
• Aluminum is an adjuvant that helps
increase the body’s immune
response  to the antigen in the
vaccine which decrease the amount
of the number  doses needed. • Aluminum is in our food, air, and
water. • Formula and breast milk
include  aluminum. • The amount of aluminum in
vaccines is  similar to that found in
975 ml of infant formula.
26
Q

Thimerosal

A
v Thimerosal is a mercury-based
preservative that has been used
to  prevent contamination of
vaccines with bacteria and fungi. v Many studies have shown that
there is no link between
thimerosal and autism.
• The form of organic mercury
contained  within thiomersal
• is ‘ethyl mercury’ which does
not accumulate in the body,
unlike the closely related
‘methyl mercury’ which does
accumulate and is neurotoxic.