Febrile Seizures Flashcards
Children with febrile seizures are more likely to have recurrent febrile seizures
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antipyretics does not decrease the risk of febrile seizures,
A febrile seizure
is a seizure occurring in a child six months to ive years of age that is accom- panied by a fever (100.4°F [38°C] or greater) with- out central nervous system infection.1 Febrile seizures are classiied as simple or complex (Table 1).1 Complex seizures last 15 minutes or more, are associated with focal neurologic ind- ings, or recur within 24 hours. Febrile seizures are the most common convulsive event in child- hood, occurring in 2% to 5% of children.
Other risk fac- tors include exposures in utero, such as maternal smoking and maternal stress;
Characteristics of Simple vs. Complex Febrile Seizures
Simple (all of the following) Duration of less than 15 minutes Generalized No previous neurologic problems Occurs once in 24 hours
Complex (any of the following) Duration of 15 minutes or more Focal neurologic signs Recurs within 24 hours
مهم anti epilepsy
Continuous or intermittent antiepileptic medi- cations are not recommended after a irst febrile seizure because of potential adverse efects.
Risk factors for recurrence
Risk factors for recurrence of febrile seizure are age younger than 18 months, fever duration of less than one hour before seizure onset, irst-degree relative with a history of febrile seizures, and a temperature of less than 104°F (40°C).
Rf
he risk of febrile seizures is related to the height of the tempera-
ture elevation, not the rate of temperature rise
Patho
-Viruses most com-
monly correlated with febrile seizures
Viral infections, particularly those associated with high fevers, increase the risk of febrile seizures because high fevers have been shown to increase neuronal excitabil-
ity and lower the seizure threshold.2
herpesvirus 6, inluenza, adenovirus, and parainluenza.7, 8
Certain vaccine preparations and associated age at administra- tion have been shown to increase the risk of febrile seizures.9 he measles-mumps-rubella vaccine is associated with an increased risk of febrile seizures
Todd paralysis
Focal neurologic signs or Todd paralysis (i.e., postictal weakness or paralysis, usually on one side of the body) should also be noted because the presence of a focal examination inding would classify the seizure as complex.18
Complication
simple febrile seizure do not have a higher risk of urinary tract infection, pneumonia, bactere-
mia, or bacterial meningitis
lumbar puncture may be considered in these patients if they are at least 12 months of age
incomplete or unknown immunization status for H. inlu- enzae type b or S. pneumoniae (because signs of meningitis may be less reliable in younger children) or if he or she was pretreated with antibiotics (this may afect the presentation of bacterial meningitis).1,24
مهم
complex febrile seizure, because complex febrile seizures are more heterogeneous. he neurologic examination is crucial when deciding whether to perform a lumbar puncture
seizures lasting longer than five minute
seizures lasting longer than ive minutes are unlikely to stop on their own, and a benzodiazepine should be administered to break the seizure.
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less than 1 Year or 2 Years with high grade fever + convulsion ➡ you should have rule out meningitis because the symptoms & signs of meningitis in children non specific ➡ LP