UWORLD meds Flashcards
sodium polystyrene sulfonate
KAYEXALATE
- used to treat hyperkalemia
- works in GI tract to trade sodium for potassium, eliminating excess in stool and decr serum levels
- *does not impact creatinine, phosphorus or calcium levels**
- must have normal bowel function to avoid the risk of intestinal necrosis assess for s/s of constipation, signs of impaction and recent bowel patterns
methotrexate
for rheumatoid arthritis
adverse effects:
bone marrow suppression (can lead to anemia, leukopenia and thrombocytopenia (characterized by petechiae, purpura and other signs of bleeding)
hepatotoxicity
GI irritation
BM suppression is managed by dose reduction or discontinuation of med
caffeine + folic acid decreases effectiveness
TERATOGENIC !!
dopamine
outcome: increases HR, BP, CO + UO
Closely monitor VS –> higher doses can lead to dangerous tachycardia and tachyarrhythmias
Tamoxifen
prescribed to pts with breast cancer and prevent reoccurance
- common side effects similar to menopause (hot flashes, vag dryness, menstrual irregularities)
- serious side effects: thromboembolic events and endometrial cancer
clopidogrel (plavix)
antiplatelet medication, should be discontinued 5-7 days before surgery to decr risk for excessive bleeding
** meds (anticoagulants, antiplatelets, NSAIDS, herbal drugs) that incr risk for bleeding should be discontinued 5-7 days before surgery)
lactulose
given to pts with liver complications such as hepatic encephalopathy (high serum ammonia levels)
med reduces the ammonia by trapping it in the gut and then expelling it
–> improved MS
antiplatelet medications
prasugrel (effient)
clopidogrel (plavix)
ticagrelor (brilinta)
niacin (nicotinic acid/B3)
used in large doses for lipid-lowering poroperties
- may produce cutaneous vessel vasodilation
transdermal fetanyl patch
indicated to treat moderate to severe CHRONIC PAIN
- not recommended to treat acute postoperative, temporary or intermittent pain as it does not provide immediate analgesia when applied
esomeprazole
long term use of PPI may decrease the absorption of calcium and promote osteoporosis
increased risk of diarrhea caused by c. diff PPIs can suppress acid that would have prevented pathogens from more easily colonizing the upper GI tract… increased risk for pneumonias
phenothioZinews
1 ND = safety + educating about s/s of infection, report to HCP
major tranquilizers
for our ZANY pts
SEs –> ABCDEFG
anticholinergic, blurred vision, constipation, drowsiness, EPS (tremors, parkinson), foto-sensitivity, aGRANULOCYTOSIS
names of tricyclic antidepressants + major info
elavil, trofranil, aventyl, desyrel
ELEVATES MOOD, HAPPY PILLS!
med takes 2-4 weeks for beneficial effects
SE of tricyclic antidepressants
ABCDE
anticholinergic (esp dry mouth) blurred vision constipation drowsiness euphoria
benzos info, uses, ending
always have ZEP in the name
valium is the prototype (induction of anesthetic, muscle relaxant, alcohol)
uses: seizures medications preop induction of anesthesia muscle relaxants etOH withdrawal med ventilation (med to relax and calm down pts on vent)
REMEMBER THESE ARE MINOR ANTIPSYCHOLITCS
“what do you find at a zeppelin concert? minors on transquilizers”
why administer major and minor antipsychotics at the same time?
major –> take longer to work
minor –> start right away
pt usually on valium and elavil at same time, then valium is discontinued
similar to heparain and coumadin
SE of benzos
ABCD anticholinergic blurred vision constipation drowsiness
MAOIs uses, teaching points, med beginning
antidepressant, thought to be caused by norepi, dopamine and serotonin in brain
all the beginnings of MAOIs rhyme “MARplan, NARdil, PARnate”
AVOID TYRAMINE-CONTAINING FOODS –> MAY CAUSE HYPERTENSIVE CRISIS
- BAR bananas, avacados, raisins
- grains except yeast
- meats - no organ liver, kidney, tripe, heart, preserved
- dairy - no cheese except mozz, cottage cheese
- no ETOH, elixers, tinctures, caffeine, chocolate, licorice, soy sauce
MAOIs SEs
*** same as benzos ABCD anticholinergic blurred vision constipation drowsiness
litium
uses, SEs
used for treating bipolar disorder, decreases mania
**se’s act more like an electrolyte - think potassium/lithium
3 P’s
peeing (polyuria)
pooping (diarhea)
parasthesia (earliest sign of electrolyte imbalance)
what is the earliest sign of electrolyte imbalance
PARESTHESIAS
NUMBNESS AND TINGLING