UW revision gonococcal disseminated 12-24 (1)

Question 1

UW table. disseminated gonococcal infection.
Manifestation? 2

Answer 1

Purulent monoarthritis
OR
Triad: tenosynovitis, dermatitis, migratory polyarthralgia

Question 2

UW table. disseminated gonococcal infection.
triad?

Answer 2

tenosynovitis, dermatitis, migratory polyarthralgia

Question 3

UW table. disseminated gonococcal infection. Dx?2

Answer 3

Detection of N. gonorrhoeae in urine, cervical or urethral sample

Culture of blood, synovial fluid (less sensitive)

Question 4

UW table. disseminated gonococcal infection. Tx?

Answer 4

i/v 3rd generation cephalosporin

Question 5

UW. disseminated gonococcal infection. diagnostics if gram stain of synovial fluid is negative?

Answer 5

Synovial fluid should be sent for nucleic acid amplification testing (NAAT) or culture [culture is usually negative = less sensitive].

Question 6

UW. disseminated gonococcal infection. additional diagnostics?

Answer 6

Mucosal sites (eg, rectum, urethra, throat) should also be sampled and specimens sent for NAAT; although patients with DGI do not typically have symptomatic infection at the portal of entry (eg, urogenital tract), mucosal NAAT is often positive and can provide a presumptive diagnosis

Question 7

UW. disseminated gonococcal infection. must to do, but low sensitivity?

Answer 7

two set of blood cultures and synovial fluid culture (if joint effusions present).

Should be sent, but low diagnostic sensitivity

Question 8

UW. disseminated gonococcal infection. Also need to screen for other STI since they occur together.

Answer 8

.

Question 9

UW. disseminated gonococcal infection. need to take samples from multiple mucosal sites (urethra, cervix, anus)

Answer 9

.