Mehlman HY bone tumors Surg + metastases 03-10 (2) Flashcards
M. what is most common primary bone tumor?
Osteosarcoma
M. Osteosarcoma. Age?
10-30 y.o
M. Osteosarcoma. what mutation is related to this cancer?
Rb - congenital retinoblastoma.
ie. 1yo boy has enucleation of eye for retinoblastoma. what is he at risk of developing later in life? A - osteosarcoma.
M. Osteosarcoma. in what other disease can occur apart retinoblastoma?
in paget disease of bone (older patients)
M. Osteosarcoma. what are 2 buzzy appearances?
Codman triangle and sunburn appearance
M. Osteosarcoma. what is codman triangle?
periosteal reaction with lifting of periosteum off the bone
M. Osteosarcoma. what is sunburst appearance?
Periosteal reaction described on NBME as ,,spiculated new bone formation”
periosteal reaction with lifting of periosteum off the bone?
codman triangle; in osteosarcoma
Periosteal reaction described on NBME as ,,spiculated new bone formation”?
sunburst appearance; in osteosarcoma
M. NBME description of osteosarcoma is ,,pleomorphic neoplastic cells producing new woven bone”
.
,pleomorphic neoplastic cells producing new woven bone”?
osteosarcoma
M. Unicameral bone cyst. underrated diagnosis. Asked in 2CK
.
M. Unicameral bone cyst. definition?
benign bone tumor that looks similar to osteosarcoma, but age of onset is usually birth to 20 yo., rather tan 20-40.
M. Unicameral bone cyst. age?
birth to 20.
M. Unicameral bone cyst. how looks like?
,,one chamber”, it is fluid-filled.
M. Unicameral bone cyst. usmle wants to know photo of this.
.
M. mestastases. usmle loves it in what site?
vertebra
M. mestastases. what origins love usmle? 3
breast, prostaste, lung
M. mestastases. usmle wont show photo is vertebral photo. they will give vignette where patient has/had cancer + lytic lesions in vertebra or neurologic syndrome (eg of cauda equina).
.
M. mestastases. what 2 components in case will be said?
diffuse bone pain + patient with background of cancer = mets
M. mestastases. if photo will show up, it will be Technetium-99 bone scan of mets.
.
M. Back pain in elderly patient with hypercalcemia –> Dx?
multiple myeloma or metastases.
M. Back in pain in patient with history of other type of cancer –> Dx?
metastases
M. Suspected spinal mets –> Dx imaging?
MRI
M. Metastases to long bones in prostate cancer –> Dx what imaging?
osteoblastic (Dx with bone scan);
spine do MRI.
